Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | EPRS1 | P07814 | 1/20 | 0.30 |
| ▸ | CFTR | P13569 | 1/20 | 0.30 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29468454 | 1.00 | HDAC6 (0.33) | HDAC6EPRS1CFTRMTNR1AMTNR1B | |
| SCHEMBL28880706 | 0.86 | HDAC6 (0.35) | HDAC6EPRS1MTNR1AMTNR1BFPR2 | |
| SCHEMBL21752293 | 0.85 | CFD (0.33) | MTNR1AMTNR1BFPR2 | |
| SCHEMBL30207179 | 0.85 | CFD (0.33) | MTNR1AMTNR1BFPR2 | |
| SCHEMBL20488090 | 0.85 | EPRS1 (0.35) | EPRS1 | |
| SCHEMBL25930645 | 0.84 | MTNR1A (0.33) | HDAC6MTNR1AMTNR1B | |
| SCHEMBL25930232 | 0.84 | MTNR1A (0.33) | HDAC6MTNR1AMTNR1BFPR2 | |
| SCHEMBL29468351 | 0.84 | MTNR1A (0.33) | HDAC6MTNR1AMTNR1BFPR2 | |
| SCHEMBL26679601 | 0.84 | AAK1 (0.31) | HDAC6MTNR1AMTNR1B | |
| SCHEMBL25959693 | 0.84 | TP53 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357199-A1 | ARYL, HETEROARYL, AND HETEROCYCLIC PHARMACEUTICAL COMPOUNDS FOR TREATMENT OF MEDICAL DISORDERS | ACHILLION PHARMACEUTICALS, INC. | 2023-11-09 | — | — | US | disclosed |
| US-11708351-B2 | Aryl, heteroaryl, and heterocyclic pharmaceutical compounds for treatment of medical disorders | ACHILLION PHARMACEUTICALS, INC. (US) | 2023-07-25 | — | — | US | disclosed |
| CN-110603252-A | Aryl, heteroaryl and heterocyclic pharmaceutical compounds for the treatment of medical disorders | 艾其林医药公司 | 2019-12-20 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11708351-B2 | Aryl, heteroaryl, and heterocyclic pharmaceutical compounds for treatment of medical disorders | CFD, TFPI, CFH | HDAC6 2840/4885EPRS1 3828/4885CFTR 529/4885 |
| US-20230357199-A1 | ARYL, HETEROARYL, AND HETEROCYCLIC PHARMACEUTICAL COMPOUNDS FOR TREATMENT OF MEDICAL DISORDERS | CFD, TFPI, CFH | HDAC6 2840/4885EPRS1 3828/4885CFTR 529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.