Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | RORA | P35398 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | RORB | Q92753 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25930711 | 0.89 | ALDH1A1 (0.42) | ALDH1A1PGRRORARORCRORB | |
| SCHEMBL25930694 | 0.87 | TDP1 (0.49) | ALDH1A1PGRRORARORCRORB | |
| SCHEMBL25930717 | 0.83 | PGR (0.43) | ALDH1A1PGRRORARORCRORB | |
| SCHEMBL25930728 | 0.83 | PGR (0.43) | ALDH1A1PGRRORARORCRORB | |
| SCHEMBL25930733 | 0.80 | ALDH1A1 (0.46) | ALDH1A1PGRRORARORCRORB | |
| SCHEMBL25972538 | 0.80 | CYP19A1 (0.52) | ALDH1A1CMA1KDM4ELMNATSHR | |
| SCHEMBL25930714 | 0.80 | ALDH1A1 (0.43) | ALDH1A1PGRRORARORCRORB | |
| SCHEMBL25930739 | 0.78 | PGR (0.43) | ALDH1A1PGRRORARORCRORB | |
| SCHEMBL17004024 | 0.76 | ALDH1A1 (0.50) | ALDH1A1PGRRORARORCRORB | |
| SCHEMBL25972542 | 0.76 | CYP19A1 (0.44) | ALDH1A1PGRRORARORCRORB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11713319-B2 | Compounds having valerolactam structures | MERCK PATENT GMBH (DE) | 2023-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11713319-B2 | Compounds having valerolactam structures | ACE, CYP3A4, CYP2D6 | ALDH1A1 165/4885PGR 818/4885RORA 301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.