Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 3/20 | 0.43 |
| ▸ | RORA | P35398 | 3/20 | 0.43 |
| ▸ | RORC | P51449 | 3/20 | 0.43 |
| ▸ | RORB | Q92753 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25930731 | 0.89 | PGR (0.50) | PGRRORARORCRORBCYP1A2 | |
| SCHEMBL25930738 | 0.84 | CYP1A2 (0.48) | PGRRORARORCRORBCYP1A2 | |
| SCHEMBL25930717 | 0.81 | PGR (0.43) | PGRRORARORCRORBCYP1A2 | |
| SCHEMBL25930728 | 0.81 | PGR (0.43) | PGRRORARORCRORBCYP1A2 | |
| SCHEMBL25930705 | 0.78 | PGR (0.43) | PGRRORARORCRORBHSD17B10 | |
| SCHEMBL25930690 | 0.78 | ALDH1A1 (0.46) | PGRRORARORCRORBTDP1 | |
| SCHEMBL25930681 | 0.78 | CYP1A2 (0.47) | PGRRORARORCRORBCYP1A2 | |
| SCHEMBL25930678 | 0.76 | PGR (0.47) | PGRRORARORCRORBCYP1A2 | |
| SCHEMBL25930735 | 0.76 | MCL1 (0.47) | PGRRORARORCRORBSMN1; SMN2 | |
| SCHEMBL9405425 | 0.76 | CYP19A1 (0.53) | CYP1A2CYP2C19TDP1L3MBTL1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11713319-B2 | Compounds having valerolactam structures | MERCK PATENT GMBH (DE) | 2023-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11713319-B2 | Compounds having valerolactam structures | ACE, CYP3A4, CYP2D6 | PGR 818/4885RORA 301/4885RORC 173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.