Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 2/20 | 0.43 |
| ▸ | RORA | P35398 | 2/20 | 0.43 |
| ▸ | RORC | P51449 | 2/20 | 0.43 |
| ▸ | RORB | Q92753 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.38 |
| ▸ | HPRT1 | P00492 | 4/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25930731 | 0.89 | PGR (0.50) | CYP1A2CYP2C19PGRRORARORC | |
| SCHEMBL25930739 | 0.84 | PGR (0.43) | CYP1A2CYP2C9CYP2C19PGRRORA | |
| SCHEMBL25930681 | 0.83 | CYP1A2 (0.47) | CYP1A2CYP2C9CYP2C19PGRRORA | |
| SCHEMBL25930709 | 0.80 | MCL1 (0.44) | CYP1A2CYP2C9CYP2C19PGRRORA | |
| SCHEMBL25930694 | 0.79 | TDP1 (0.49) | CYP1A2CYP2C9CYP2C19PGRRORA | |
| SCHEMBL25930678 | 0.79 | PGR (0.47) | CYP1A2CYP2C9CYP2C19PGRRORA | |
| SCHEMBL25930717 | 0.78 | PGR (0.43) | CYP1A2CYP2C9CYP2C19PGRRORA | |
| SCHEMBL25930705 | 0.78 | PGR (0.43) | PGRRORARORCRORBHSD17B10 | |
| SCHEMBL25930714 | 0.77 | ALDH1A1 (0.43) | CYP1A2CYP2C9CYP2C19PGRRORA | |
| SCHEMBL9405425 | 0.76 | CYP19A1 (0.53) | CYP1A2CYP2C19TDP1HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11713319-B2 | Compounds having valerolactam structures | MERCK PATENT GMBH (DE) | 2023-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11713319-B2 | Compounds having valerolactam structures | ACE, CYP3A4, CYP2D6 | CYP1A2 32/4885CYP2C9 6/4885CYP2C19 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.