Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL20984941 | 0.98 | ALDH1A1 (0.41) | ALDH1A1MAPTKMT2AKDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL20984506 | 0.98 | ALDH1A1 (0.42) | ALDH1A1MAPTKMT2AKDM4ESMN1; SMN2 | |
| Sulfuric Acid SCHEMBL20984874 | 0.90 | NFE2L2 (0.42) | ALDH1A1KMT2ACA12CA1CA2 | |
| SCHEMBL8795380 | 0.83 | ALDH1A1 (0.44) | ALDH1A1MAPTKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL8139679 | 0.82 | ALDH1A1 (0.44) | ALDH1A1MAPTKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL21893783 | 0.82 | APP (0.43) | ALDH1A1MAPTKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL11415861 | 0.80 | JAK2 (0.43) | ALDH1A1MAPTKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL126417 | 0.79 | ALDH1A1 (0.55) | ALDH1A1MAPTKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL29457620 | 0.79 | ALDH1A1 (0.55) | ALDH1A1MAPTKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL3790244 | 0.78 | CA1 (0.58) | ALDH1A1MAPTKDM4ESMN1; SMN2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023144332-A1 | TETRAHYDROPYRANOPYRAZOLE DERIVATIVES FOR THE TREATMENT OF CANCER AND VIRAL INFECTIONS | GENASE THERAPEUTICS B.V. (NL) | 2023-08-03 | — | — | WO | disclosed |