Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.41 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30493371 | 1.00 | GPR119 (0.44) | GPR119PDE4BLMNATP53THRB | |
| SCHEMBL25931020 | 1.00 | GPR119 (0.44) | GPR119PDE4BLMNATP53THRB | |
| SCHEMBL25931356 | 1.00 | GPR119 (0.44) | GPR119PDE4BLMNATP53THRB | |
| SCHEMBL25331509 | 0.88 | CHRM4 (0.41) | LMNATP53ALDH1A1 | |
| SCHEMBL15442067 | 0.80 | GPR119 (0.64) | GPR119LMNAALDH1A1 | |
| SCHEMBL13279217 | 0.78 | SMARCA2 (0.52) | GPR119LMNATP53THRBABCB1 | |
| SCHEMBL15442285 | 0.78 | SMARCA2 (0.52) | GPR119LMNATP53THRBABCB1 | |
| SCHEMBL7364745 | 0.78 | SMARCA2 (0.52) | GPR119LMNATP53THRBABCB1 | |
| SCHEMBL652991 | 0.77 | MEN1 (0.53) | GPR119LMNASMARCA2SMARCA4PBRM1 | |
| SCHEMBL656085 | 0.77 | MEN1 (0.53) | GPR119LMNASMARCA2SMARCA4PBRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023139199-A1 | COMPOUNDS AND THEIR USE IN TREATING CANCER | ASTRAZENECA AB (SE) | 2023-07-27 | — | — | WO | disclosed |