Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GFER | P55789 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ADAMTS5 | Q9UNA0 | 5/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30493371 | 0.88 | GPR119 (0.44) | ALDH1A1LMNATP53 | |
| SCHEMBL25931356 | 0.88 | GPR119 (0.44) | ALDH1A1LMNATP53 | |
| SCHEMBL25931020 | 0.88 | GPR119 (0.44) | ALDH1A1LMNATP53 | |
| SCHEMBL25931015 | 0.88 | GPR119 (0.44) | ALDH1A1LMNATP53 | |
| SCHEMBL17746120 | 0.73 | MAPT (0.47) | GFERMEN1KMT2ALMNAMAPT | |
| SCHEMBL6904992 | 0.73 | MAPK1 (0.55) | SLC18A3GFERLMNAMAPTADAMTS5 | |
| SCHEMBL6912788 | 0.72 | GFER (0.46) | GFERMEN1KMT2ALMNAMAPT | |
| SCHEMBL27208470 | 0.72 | GFER (0.46) | GFERMEN1KMT2ALMNAMAPT | |
| SCHEMBL27208320 | 0.72 | GFER (0.46) | GFERMEN1KMT2ALMNAMAPT | |
| SCHEMBL29656929 | 0.71 | ALDH1A1 (0.45) | SLC18A3ALDH1A1GFERMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023139199-A1 | COMPOUNDS AND THEIR USE IN TREATING CANCER | ASTRAZENECA AB (SE) | 2023-07-27 | — | — | WO | disclosed |