Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.38 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.38 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2799978 | 0.89 | NUDT1 (0.51) | NUDT1ALDH1A1HSD17B10PDE4APDE4B | |
| SCHEMBL10829083 | 0.85 | TDP1 (0.44) | ALDH1A1HSD17B10ADORA2AADORA1TDP1 | |
| SCHEMBL29277891 | 0.84 | RAB9A (0.46) | ALDH1A1HSD17B10ADORA2AADORA1TDP1 | |
| SCHEMBL30714452 | 0.84 | RAB9A (0.46) | ALDH1A1HSD17B10ADORA2AADORA1TDP1 | |
| SCHEMBL6586695 | 0.83 | NUDT1 (0.47) | NUDT1ALDH1A1HSD17B10PDE4APDE4B | |
| SCHEMBL30818025 | 0.83 | NUDT1 (0.47) | NUDT1ALDH1A1HSD17B10PDE4APDE4B | |
| SCHEMBL29430975 | 0.80 | MAOB (0.46) | NUDT1ALDH1A1HSD17B10PDE4APDE4B | |
| SCHEMBL18582910 | 0.80 | NUDT1 (0.45) | NUDT1ALDH1A1HSD17B10PDE4APDE4B | |
| SCHEMBL6573071 | 0.79 | ALDH1A1 (0.54) | ALDH1A1HSD17B10TDP1TP53CYP3A4 | |
| SCHEMBL3923680 | 0.78 | HSD17B10 (0.50) | ALDH1A1HSD17B10PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242512-A1 | ISOINDOLINES AS HDAC INHIBITORS | VALO HEALTH, INC. | 2023-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242512-A1 | ISOINDOLINES AS HDAC INHIBITORS | HDAC1, HDAC2, HDAC3 | NUDT1 4570/4885ALDH1A1 1133/4885HSD17B10 823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.