Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 4/20 | 0.40 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | PARP3 | Q9Y6F1 | 2/20 | 0.39 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.39 |
| ▸ | TNKS | O95271 | 2/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.37 |
| ▸ | WNT3A | P56704 | 2/20 | 0.36 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.36 |
| ▸ | AXIN2 | Q9Y2T1 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15672303 | 0.86 | TNKS2 (0.40) | TNKS2PARP1PARP3PARP15TNKS | |
| SCHEMBL20286634 | 0.83 | TNKS2 (0.46) | TNKS2PARP1PARP3PARP15TNKS | |
| SCHEMBL15315468 | 0.82 | TNKS2 (0.56) | TNKS2PARP1PARP3TNKSPDK1 | |
| SCHEMBL5734981 | 0.79 | ALDH1A1 (0.42) | BCHEACHEMAPTKDM4EALDH1A1 | |
| SCHEMBL6075839 | 0.79 | KDM4E (0.44) | ALOX5ACHEMAPTKDM4EALDH1A1 | |
| SCHEMBL15921414 | 0.72 | PDE4B (0.34) | TNKS2PARP1PARP3PARP15TNKS | |
| SCHEMBL16179473 | 0.70 | PDE4B (0.38) | MAPTKDM4E | |
| SCHEMBL27443057 | 0.68 | PARP1 (0.40) | TNKS2PARP1PARP3PARP15TNKS | |
| SCHEMBL13231717 | 0.66 | L3MBTL1 (0.50) | MEN1KMT2AADORA3ACHEALDH1A1 | |
| SCHEMBL5742540 | 0.65 | MEN1 (0.47) | MEN1KMT2ABCHEMTORACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230220337-A1 | METHOD OF MICROGLIA DIFFERENTIATION CAPABLE OF SECURING LARGE QUANTITY OF MICROGLIA BY USING 3D ORGANOIDS FROM HUMAN PLURIPOTENT STEM CELLS | CORESTEM CO.,LTD. (KR) | 2023-07-13 | — | — | US | disclosed |