Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | PARP3 | Q9Y6F1 | 2/20 | 0.40 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | TNKS | O95271 | 2/20 | 0.31 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.31 |
| ▸ | WNT3A | P56704 | 1/20 | 0.31 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.31 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.31 |
| ▸ | AXIN2 | Q9Y2T1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30870656 | 1.00 | PARP1 (0.40) | PARP1PARP3PARP15PDK1TNKS | |
| SCHEMBL14843250 | 0.81 | PARP1 (0.42) | PARP1PARP3PARP15PDK1TNKS | |
| SCHEMBL24697998 | 0.72 | ACHE (0.40) | — | |
| SCHEMBL8574606 | 0.72 | ACHE (0.41) | — | |
| SCHEMBL25932351 | 0.68 | TNKS2 (0.40) | PARP1PARP3PARP15PDK1TNKS | |
| SCHEMBL15315468 | 0.66 | TNKS2 (0.56) | PARP1PARP3PDK1TNKSTNKS2 | |
| SCHEMBL29411302 | 0.66 | TNKS2 (0.56) | PARP1PARP3PDK1TNKSTNKS2 | |
| SCHEMBL24954134 | 0.62 | PARP1 (0.50) | PARP1PARP3PARP15TNKSTNKS2 | |
| SCHEMBL13982645 | 0.61 | — | — | |
| SCHEMBL14843025 | 0.61 | ALDH1A1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024086246-A2 | 2-SUBSTITUTED 3,4 A, 5, 7, 8, 8 A-HEXAHYDRO-4H-THIOP YRANO [4,3- DJPYRIMIDIN-4-ONES FOR WOUND TREATMENT | Eluciderm Inc. (US) | 2024-04-25 | — | — | WO | disclosed |