Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17057475 | 1.00 | TOP1 (0.86) | TOP1SLC2A1 | |
| Lurtotecan SCHEMBL13992 | 0.92 | TOP1 (1.00) | TOP1SLC2A1 | |
| Lurtotecan SCHEMBL19208 | 0.92 | TOP1 (1.00) | TOP1SLC2A1 | |
| Lurtotecan SCHEMBL29774186 | 0.92 | TOP1 (1.00) | TOP1SLC2A1 | |
| Lurtotecan SCHEMBL29379042 | 0.92 | TOP1 (0.98) | TOP1SLC2A1 | |
| Lurtotecan SCHEMBL1649335 | 0.92 | TOP1 (0.98) | TOP1SLC2A1 | |
| Lurtotecan SCHEMBL1649336 | 0.91 | TOP1 (0.97) | TOP1SLC2A1 | |
| SCHEMBL13928539 | 0.89 | TOP1 (0.82) | TOP1SLC2A1 | |
| SCHEMBL26843277 | 0.89 | TOP1 (0.82) | TOP1SLC2A1 | |
| SCHEMBL31312371 | 0.88 | TOP1 (1.00) | TOP1SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230241241-A1 | CONJUGATES OF A CELL-BINDING MOLECULE WITH CAMPTOTHECIN ANALOGS | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2023-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230241241-A1 | CONJUGATES OF A CELL-BINDING MOLECULE WITH CAMPTOTHECIN ANALOGS | CD4, DCLRE1A, TOP1 | TOP1 3/4885SLC2A1 3139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.