Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25932537 | 1.00 | TOP1 (0.86) | TOP1SLC2A1 | |
| Lurtotecan SCHEMBL13992 | 0.92 | TOP1 (1.00) | TOP1SLC2A1 | |
| Lurtotecan SCHEMBL19208 | 0.92 | TOP1 (1.00) | TOP1SLC2A1 | |
| Lurtotecan SCHEMBL29774186 | 0.92 | TOP1 (1.00) | TOP1SLC2A1 | |
| Lurtotecan SCHEMBL29379042 | 0.92 | TOP1 (0.98) | TOP1SLC2A1 | |
| Lurtotecan SCHEMBL1649335 | 0.92 | TOP1 (0.98) | TOP1SLC2A1 | |
| Lurtotecan SCHEMBL1649336 | 0.91 | TOP1 (0.97) | TOP1SLC2A1 | |
| SCHEMBL13928539 | 0.89 | TOP1 (0.82) | TOP1SLC2A1 | |
| SCHEMBL26843277 | 0.89 | TOP1 (0.82) | TOP1SLC2A1 | |
| SCHEMBL31312371 | 0.88 | TOP1 (1.00) | TOP1SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015128837-A1 | METHODS OF TREATING CANCER PATIENTS RESPONDING TO EZH2 INHIBITOR GSK126 | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2015-09-03 | — | — | WO | disclosed |