SCHEMBL25933458

SCHEMBL25933458

Oc1ccc(C(c2ccc(O)c(CC(F)(F)F)c2)(C(F)(F)F)C(F)(F)F)cc1

nearest known ligand 0.58

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 9/20 0.58
ESR2 Q92731 7/20 0.58
KLF10 Q13118 1/20 0.38
KIF11 P52732 1/20 0.35
CYP2D6 P10635 2/20 0.35
EGFR P00533 1/20 0.33
CACNA1B Q00975 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2300766 0.80 ESR1 (0.53) ESR1ESR2KLF10
SCHEMBL4560440 0.76 ESR1 (1.00) ESR1ESR2KIF11
SCHEMBL21027 0.76 ESR1 (1.00) ESR1ESR2KIF11
SCHEMBL3686864 0.76 ESR1 (1.00) ESR1ESR2KIF11
SCHEMBL13185901 0.76 ESR1 (0.67) ESR1ESR2KIF11
SCHEMBL20958252 0.76 ESR1 (0.65) ESR1ESR2KLF10CYP2D6CACNA1B
SCHEMBL29785649 0.75 ESR1 (0.64) ESR1ESR2KIF11
SCHEMBL25933574 0.75 ESR1 (0.64) ESR1ESR2KIF11
Potassium SCHEMBL30701764 0.74 ESR1 (0.95) ESR1ESR2KIF11
SCHEMBL30625966 0.74 ESR1 (0.95) ESR1ESR2KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230244148-A1 EUV RESIST UNDERLAYER FILM-FORMING COMPOSITION NISSAN CHEMICAL CORPORATION (JP) 2023-08-03 US disclosed
US-20230244148-A1 EUV RESIST UNDERLAYER FILM-FORMING COMPOSITION NISSAN CHEMICAL CORPORATION (JP) 2023-08-03 US disclosed