Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10654709 | 0.80 | TSHR (0.53) | ALDH1A1MEN1KMT2AMAPTSLC6A2 | |
| SCHEMBL5248985 | 0.78 | CYP1A2 (0.59) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL29274258 | 0.77 | RAB9A (0.50) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL29274252 | 0.77 | KMT2A (0.51) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| Methoxymethane SCHEMBL27522023 | 0.77 | CYP1A2 (0.54) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL40607 | 0.76 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2AHSD17B10SIGMAR1 | |
| SCHEMBL29374664 | 0.74 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2AMAPTHSD17B10 | |
| SCHEMBL9311036 | 0.74 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2AMAPTHSD17B10 | |
| SCHEMBL25933629 | 0.73 | SLC6A2 (0.46) | ALDH1A1MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL25250134 | 0.73 | PDE7A (0.66) | ALDH1A1MEN1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242502-A1 | THIOBENZOPYRANS AND THEIR USE IN PREPARATION OF DRUGS FOR TREATMENT OF RHEUMATOID ARTHRITIS | HC Synthetic Pharmaceutical Co., Ltd. (CN) | 2023-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242502-A1 | THIOBENZOPYRANS AND THEIR USE IN PREPARATION OF DRUGS FOR TREATMENT OF RHEUMATOID ARTHRITIS | TST, SSB, HK1 | ALDH1A1 818/4885MEN1 4865/4885KMT2A 2785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.