SCHEMBL25933730

SCHEMBL25933730

Bc1ccc2nc(C)cnc2n1

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.31
MET P08581 1/20 0.31
CCNB2 O95067 1/20 0.30
CDK1 P06493 1/20 0.30
CCNB1 P14635 1/20 0.30
CDK5 Q00535 1/20 0.30
CDK5R1 Q15078 1/20 0.30
CCNB3 Q8WWL7 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
MAPK1 P28482 1/20 0.30
HTT P42858 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
ADRA2A P08913 1/20 0.30
ADRA2B P18089 1/20 0.30
ADRA2C P18825 1/20 0.30
ADRA1D P25100 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24284152 0.81 CYP1A2 (0.43) CYP1A2ALDH1A1
SCHEMBL25106981 0.76 BACE1 (0.41) CYP1A2METALDH1A1
SCHEMBL2629404 0.69 BCHE (0.42) CYP1A2METALDH1A1
SCHEMBL9797853 0.68 CCNB2 (0.33) CCNB2CDK1CCNB1CDK5CDK5R1
SCHEMBL18530908 0.68 CCNB2 (0.37) CYP1A2CCNB2CDK1CCNB1CDK5
SCHEMBL14644342 0.68 MET (0.33) METCCNB2CDK1CCNB1CDK5
SCHEMBL14200141 0.67 KDM4E (0.35) CYP1A2CCNB2CDK1CCNB1CDK5
SCHEMBL12910655 0.66 CYP1A2 (0.40) CYP1A2CCNB2CDK1CCNB1CDK5
SCHEMBL14200138 0.65 KDM4E (0.34) CYP1A2CCNB2CDK1CCNB1CDK5
SCHEMBL22057563 0.64 ALDH1A1 (0.47) CYP1A2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3960733-B1 BENZOCARBAZOLE-BASED COMPOUNDS AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING THEM LG CHEMICAL LTD (KR) 2023-08-09 EP disclosed