Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 9/20 | 0.84 |
| ▸ | LMNA | P02545 | 9/20 | 0.84 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.84 |
| ▸ | MAPT | P10636 | 6/20 | 0.84 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.84 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.84 |
| ▸ | SHBG | P04278 | 4/20 | 0.84 |
| ▸ | SERPINA6 | P08185 | 4/20 | 0.84 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.84 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.84 |
| ▸ | TSHR | P16473 | 5/20 | 0.78 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.78 |
| ▸ | PGR | P06401 | 5/20 | 0.78 |
| ▸ | AR | P10275 | 4/20 | 0.78 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.78 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.78 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.78 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.78 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.78 |
| ▸ | MEN1 | O00255 | 2/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2169764 | 1.00 | CYP3A4 (0.84) | CYP3A4LMNAALDH1A1MAPTSMN1; SMN2 | |
| Desoxycorticosterone SCHEMBL25773308 | 0.91 | LMNA (1.00) | CYP3A4LMNAALDH1A1MAPTSMN1; SMN2 | |
| Desoxycorticosterone SCHEMBL4065 | 0.91 | LMNA (1.00) | CYP3A4LMNAALDH1A1MAPTSMN1; SMN2 | |
| Desoxycorticosterone SCHEMBL28269906 | 0.91 | LMNA (1.00) | CYP3A4LMNAALDH1A1MAPTSMN1; SMN2 | |
| Desoxycorticosterone SCHEMBL13752803 | 0.91 | LMNA (1.00) | CYP3A4LMNAALDH1A1MAPTSMN1; SMN2 | |
| Desoxycorticosterone SCHEMBL15763287 | 0.91 | LMNA (1.00) | CYP3A4LMNAALDH1A1MAPTSMN1; SMN2 | |
| Desoxycorticosterone SCHEMBL18891475 | 0.91 | LMNA (1.00) | CYP3A4LMNAALDH1A1MAPTSMN1; SMN2 | |
| Desoxycorticosterone SCHEMBL21243062 | 0.91 | LMNA (1.00) | CYP3A4LMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL22732246 | 0.91 | LMNA (0.84) | CYP3A4LMNAALDH1A1MAPTSMN1; SMN2 | |
| Desoxycorticosterone SCHEMBL4066 | 0.91 | LMNA (1.00) | CYP3A4LMNAALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230250131-A1 | HYDROXYSTEROID COMPOUNDS | EPIRIUM BIO INC (US) | 2023-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230250131-A1 | HYDROXYSTEROID COMPOUNDS | HSD3B2, HSD11B1, HSD3B1 | CYP3A4 132/4885LMNA 2148/4885ALDH1A1 1405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.