Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGMN | Q99538 | 1/20 | 0.49 |
| ▸ | SYK | P43405 | 11/20 | 0.45 |
| ▸ | BTK | Q06187 | 5/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | ROS1 | P08922 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.40 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 2/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29728069 | 0.83 | SYK (0.59) | SYKBTKPDGFRBPDGFRAJAK2 | |
| SCHEMBL18399012 | 0.83 | SYK (0.59) | SYKBTKPDGFRBPDGFRAJAK2 | |
| SCHEMBL30837522 | 0.82 | NOS1 (0.52) | SYKBTKPDGFRBPDGFRANOS1 | |
| SCHEMBL29039315 | 0.79 | NOS1 (0.49) | SYKBTKPDGFRBPDGFRANOS1 | |
| SCHEMBL30385421 | 0.79 | NOS1 (0.49) | SYKBTKPDGFRBPDGFRANOS1 | |
| SCHEMBL30469212 | 0.78 | TERT (0.53) | SYKBTKPDGFRBPDGFRANOS1 | |
| SCHEMBL29539832 | 0.77 | PDGFRB (0.55) | SYKBTKPDGFRBPDGFRANOS1 | |
| SCHEMBL2799745 | 0.77 | PDGFRB (0.55) | SYKBTKPDGFRBPDGFRANOS1 | |
| SCHEMBL5095062 | 0.76 | FGFR1 (0.56) | BTKPDGFRBPDGFRAJAK2NTRK1 | |
| SCHEMBL5412781 | 0.73 | PLK4 (0.56) | SYKBTKPDGFRBPDGFRAPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109892-A1 | COMPOUND FOR INHIBITING OR DEGRADING BRD9, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF | 海思科医药集团股份有限公司 | 2023-06-22 | — | — | WO | disclosed |