Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 2/20 | 0.37 |
| ▸ | MMP13 | P45452 | 11/20 | 0.37 |
| ▸ | MMP1 | P03956 | 8/20 | 0.37 |
| ▸ | MMP2 | P08253 | 5/20 | 0.37 |
| ▸ | MMP3 | P08254 | 5/20 | 0.37 |
| ▸ | MMP8 | P22894 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 6/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | MMP7 | P09237 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MMP10 | P09238 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25317994 | 0.90 | RAB9A (0.40) | RAB9ACYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL26023163 | 0.90 | MMP13 (0.40) | RAB9ACYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL30507123 | 0.90 | RAB9A (0.40) | RAB9ACYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL25313592 | 0.90 | RAB9A (0.38) | RAB9ACYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL30506855 | 0.90 | RAB9A (0.38) | RAB9ACYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL25314065 | 0.78 | RAB9A (0.43) | RAB9ACYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL30507020 | 0.78 | RAB9A (0.43) | RAB9ACYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL26036191 | 0.75 | MMP9 (0.43) | BACE1MMP13MMP1MMP9ADAM17 | |
| SCHEMBL25320520 | 0.72 | CYP3A4 (0.53) | CYP3A4CYP2C9PKMCYP2C19MMP13 | |
| SCHEMBL26027425 | 0.72 | MMP13 (0.63) | CYP3A4CYP2C9PKMCYP2C19MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141432-A2 | APOL1 INHIBITORS AND METHODS OF USE | MAZE THERAPEUTICS, INC. (US) | 2023-07-27 | — | — | WO | disclosed |