Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | ANPEP | P15144 | 1/20 | 0.47 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.43 |
| ▸ | ADH1B | P00325 | 2/20 | 0.43 |
| ▸ | ADH1C | P00326 | 2/20 | 0.43 |
| ▸ | ADH1A | P07327 | 2/20 | 0.43 |
| ▸ | ADH4 | P08319 | 2/20 | 0.43 |
| ▸ | ADH7 | P40394 | 2/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25781929 | 0.96 | TSHR (0.48) | TSHRALDH1A1ANPEPERAP2CYP3A4 | |
| SCHEMBL9202558 | 0.96 | ALDH1A1 (0.54) | TSHRALDH1A1ANPEPERAP2CYP3A4 | |
| SCHEMBL22861921 | 0.92 | ALDH1A1 (0.50) | TSHRALDH1A1ANPEPERAP2CYP3A4 | |
| SCHEMBL9212067 | 0.91 | ALDH1A1 (0.59) | TSHRALDH1A1ANPEPERAP2CYP3A4 | |
| SCHEMBL26741304 | 0.91 | TSHR (0.52) | TSHRALDH1A1ANPEPERAP2CYP3A4 | |
| SCHEMBL26741197 | 0.91 | TSHR (0.52) | TSHRALDH1A1ANPEPERAP2CYP3A4 | |
| SCHEMBL9206325 | 0.91 | ALDH1A1 (0.58) | TSHRALDH1A1ANPEPERAP2CYP3A4 | |
| SCHEMBL24673319 | 0.90 | ALDH1A1 (0.53) | TSHRALDH1A1ANPEPERAP2CYP3A4 | |
| SCHEMBL29107020 | 0.89 | ALDH1A1 (0.56) | TSHRALDH1A1ANPEPERAP2CYP3A4 | |
| SCHEMBL25933010 | 0.89 | ALDH1A1 (0.50) | TSHRALDH1A1ANPEPERAP2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11712467-B2 | Methods of rational nicotine hapten design and uses thereof | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2023-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11712467-B2 | Methods of rational nicotine hapten design and uses thereof | NAPRT, CHRNG, CHRNB2 | TSHR 1406/4885ALDH1A1 655/4885ANPEP 1087/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.