SCHEMBL25935190

SCHEMBL25935190

CC1(C)OB(c2cccc3c2C=CC(O)N3)OC1(C)C

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ LPL P06858 1/20 0.30
▸ LIPG Q9Y5X9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20595112 0.72 PGR (0.34) LPLLIPG
SCHEMBL29789650 0.72 PGR (0.34) LPLLIPG
SCHEMBL17072956 0.71 GAA (0.47) LPLLIPG
SCHEMBL5899734 0.65 LPL (0.54) LPLLIPG
SCHEMBL31565434 0.64 CREBBP (0.59) —
SCHEMBL19518333 0.64 CREBBP (0.59) —
SCHEMBL17673172 0.64 CREBBP (0.59) —
SCHEMBL11927624 0.64 LPL (0.44) LPLLIPG
SCHEMBL13527502 0.64 LPL (0.44) LPLLIPG
SCHEMBL17072824 0.64 MAPT (0.44) LPLLIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230234935-A1 KINASE INHIBITOR COMPOUNDS AND COMPOSITIONS AND METHODS OF USE ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI 2023-07-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230234935-A1 KINASE INHIBITOR COMPOUNDS AND COMPOSITIONS AND METHODS OF USE PACSIN2, MAP3K20, PHKG1 LPL 808/4885LIPG 783/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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