Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | ALPL | P05186 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | PDE3B | Q13370 | 5/20 | 0.51 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.51 |
| ▸ | PDE4A | P27815 | 3/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.51 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.50 |
| ▸ | METAP2 | P50579 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10353474 | 0.86 | MAPT (0.80) | MAPTLMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL3452908 | 0.84 | LMNA (0.80) | MAPTLMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL24732040 | 0.81 | LMNA (0.60) | MAPTLMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL9815929 | 0.81 | MAPT (0.97) | MAPTLMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL11035831 | 0.79 | LMNA (1.00) | MAPTLMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL7302713 | 0.79 | MAPT (0.66) | MAPTLMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL1640658 | 0.79 | MAPT (0.66) | MAPTLMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL10969675 | 0.78 | LMNA (0.69) | MAPTLMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL3109943 | 0.78 | CYP1A2 (0.59) | MAPTLMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL9687063 | 0.77 | LMNA (0.69) | MAPTLMNAMEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109892-A1 | COMPOUND FOR INHIBITING OR DEGRADING BRD9, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF | 海思科医药集团股份有限公司 | 2023-06-22 | — | — | WO | disclosed |