Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.97 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RARB | P10826 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | RARA | P10276 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10353474 | 0.88 | MAPT (0.80) | MAPTLMNAMEN1KMT2AHRH3 | |
| SCHEMBL8114174 | 0.84 | MAPT (0.74) | MAPTLMNAMEN1KMT2AHRH3 | |
| Bromide SCHEMBL8100497 | 0.82 | MAPT (0.72) | MAPTLMNAMEN1KMT2AHRH3 | |
| SCHEMBL25935974 | 0.81 | MAPT (0.69) | MAPTLMNAMEN1KMT2AHRH3 | |
| Bromide SCHEMBL8108897 | 0.81 | MAPT (0.69) | MAPTLMNAMEN1KMT2AHRH3 | |
| SCHEMBL7302713 | 0.78 | MAPT (0.66) | MAPTLMNAMEN1KMT2AHRH3 | |
| SCHEMBL1640658 | 0.78 | MAPT (0.66) | MAPTLMNAMEN1KMT2AHRH3 | |
| SCHEMBL10196775 | 0.78 | HRH3 (0.66) | MAPTLMNAMEN1KMT2AHRH3 | |
| SCHEMBL3452908 | 0.77 | LMNA (0.80) | MAPTLMNAMEN1KMT2AHRH3 | |
| SCHEMBL11707234 | 0.74 | MAPT (0.56) | MAPTGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0160416-B1 | SUBSTITUTED PYRIDAZINES | Chisso Corporation (JP) | 1991-09-11 | — | — | EP | disclosed |
| US-4657695-A | FERROELECTRIC LIQUIDS CRYSTALS | CHISSO CORPORATION (JP) | 1987-04-14 | — | — | US | disclosed |
| EP-0160416-A2 | Substituted pyridazines | Chisso Corporation (JP) | 1985-11-06 | — | — | EP | disclosed |