Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.65 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | ACACA | Q13085 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 2/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL187113 | 0.95 | CYP4F2 (0.71) | CYP4F2CYP4A11HTTPKMTHRB | |
| SCHEMBL31108899 | 0.95 | CYP4F2 (0.71) | CYP4F2CYP4A11HTTPKMTHRB | |
| SCHEMBL186368 | 0.95 | CYP4F2 (0.71) | CYP4F2CYP4A11HTTPKMTHRB | |
| SCHEMBL3279755 | 0.95 | CYP4F2 (0.71) | CYP4F2CYP4A11HTTPKMTHRB | |
| SCHEMBL185905 | 0.93 | CYP4F2 (0.68) | CYP4F2CYP4A11HTTPKMTHRB | |
| SCHEMBL186940 | 0.90 | CYP4F2 (0.65) | CYP4F2CYP4A11HTTPKMTHRB | |
| SCHEMBL187405 | 0.89 | CYP4F2 (0.63) | CYP4F2CYP4A11HTTPKMTHRB | |
| SCHEMBL31108865 | 0.89 | CYP4F2 (0.63) | CYP4F2CYP4A11HTTPKMTHRB | |
| SCHEMBL3286744 | 0.89 | CYP4F2 (0.63) | CYP4F2CYP4A11HTTPKMTHRB | |
| SCHEMBL3278285 | 0.87 | CYP4F2 (0.60) | CYP4F2CYP4A11HTTPKMTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11760714-B2 | Methods of making bempedoic acid and compositions of the same | ESPERION THERAPEUTICS, INC. (US) | 2023-09-19 | — | — | US | disclosed |
| US-20230250043-A1 | METHODS OF MAKING BEMPEDOIC ACID AND COMPOSITIONS OF THE SAME | GLAS AMERICAS LLC | 2023-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230250043-A1 | METHODS OF MAKING BEMPEDOIC ACID AND COMPOSITIONS OF THE SAME | ALOX5, ALOX15, CYP27A1 | CYP4F2 195/4885CYP4A11 53/4885HTT 101/4885 |
| US-11760714-B2 | Methods of making bempedoic acid and compositions of the same | ALOX5, ALOX15, CYP27A1 | CYP4F2 195/4885CYP4A11 53/4885HTT 101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.