Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SLC6A1 | P30531 | 4/20 | 0.43 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3681679 | 0.93 | NPSR1 (0.41) | KMT2ASLC6A1KDM2BTSHRSLC6A2 | |
| SCHEMBL10367522 | 0.82 | ALDH1A1 (0.47) | KMT2AKDM2BHSD17B10ALDH1A1KDM4E | |
| SCHEMBL2996246 | 0.80 | AKR1C3 (0.46) | KMT2ASLC6A1KDM2BSLC6A2SLC6A4 | |
| SCHEMBL2996249 | 0.80 | AKR1C3 (0.46) | KMT2ASLC6A1KDM2BSLC6A2SLC6A4 | |
| SCHEMBL2996251 | 0.80 | AKR1C3 (0.46) | KMT2ASLC6A1KDM2BSLC6A2SLC6A4 | |
| SCHEMBL23579159 | 0.78 | NPC1 (0.56) | KMT2AHSD17B10TSHRALDH1A1KDM4E | |
| SCHEMBL5729067 | 0.76 | NPC1 (0.58) | KMT2ATSHRALDH1A1CYP2C19 | |
| SCHEMBL1363420 | 0.76 | TSHR (0.64) | KMT2AHSD17B10TSHRALDH1A1KDM4E | |
| SCHEMBL3389632 | 0.76 | KDM2B (0.57) | KDM2BTSHRALDH1A1HPGD | |
| SCHEMBL5451947 | 0.76 | ALDH1A1 (0.56) | KMT2AALDH1A1KDM4EHPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11718578-B2 | Ketamine flow synthesis | Université de Liège (BE) | 2023-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11718578-B2 | Ketamine flow synthesis | OPRL1, HTR4, KCNQ4 | KMT2A 1211/4885SLC6A1 405/4885KDM2B 918/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.