Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | CPB1 | P15086 | 1/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3027381 | 0.98 | ALDH1A1 (0.54) | ALDH1A1ALOX15CPB1SRD5A2HPGD | |
| SCHEMBL5462752 | 0.96 | ALDH1A1 (0.56) | ALDH1A1ALOX15CPB1SRD5A2HPGD | |
| Phthalic Acid SCHEMBL27732928 | 0.84 | ALDH1A1 (0.56) | ALDH1A1ALOX15CPB1SRD5A2HPGD | |
| SCHEMBL8536616 | 0.83 | ALDH1A1 (0.50) | ALDH1A1ALOX15CPB1HPGDAKR1C3 | |
| SCHEMBL8536613 | 0.83 | ALDH1A1 (0.50) | ALDH1A1ALOX15CPB1HPGDAKR1C3 | |
| SCHEMBL29004698 | 0.81 | ALDH1A1 (0.52) | ALDH1A1ALOX15CPB1HPGDAKR1C3 | |
| Phthalic Acid SCHEMBL30731306 | 0.81 | ALDH1A1 (0.52) | ALDH1A1ALOX15CPB1HPGDAKR1C3 | |
| Phthalic Acid SCHEMBL27812813 | 0.81 | ALDH1A1 (0.52) | ALDH1A1ALOX15CPB1HPGDAKR1C3 | |
| SCHEMBL3389632 | 0.80 | KDM2B (0.57) | ALDH1A1HPGDGAARAB9AMAPT | |
| SCHEMBL10405163 | 0.79 | ALDH1A1 (0.45) | ALDH1A1SRD5A2HPGDGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018414-A2 | ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | claimed |
| US-20070191420-A1 | Kinase inhibitors | DEVGEN NV | 2007-08-16 | — | — | US | disclosed |
| EP-1715862-A1 | KINASE INHIBITORS | Devgen NV (BE) | 2006-11-02 | — | — | EP | disclosed |
| WO-2005082367-A1 | KINASE INHIBITORS | DEVGEN NV (BE) | 2005-09-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191420-A1 | Kinase inhibitors | ROCK1, ROCK2, MAP3K20 | ALDH1A1 4377/4885ALOX15 3562/4885CPB1 3529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.