Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3410569 | 0.90 | FOLH1 (0.43) | PPARGCYP4F2CYP4A11LMNAPKM | |
| SCHEMBL25911838 | 0.89 | SMN1; SMN2 (0.45) | PPARGSMN1; SMN2CYP4F2CYP4A11LMNA | |
| SCHEMBL2390130 | 0.85 | CYP4F2 (0.51) | PPARGSMN1; SMN2CYP4F2CYP4A11LMNA | |
| SCHEMBL11291420 | 0.84 | NR1H4 (0.55) | NR1H4KDM4EALDH1A1HPGDPDCD1 | |
| SCHEMBL23425638 | 0.83 | TRPM8 (0.48) | SMN1; SMN2CYP4F2CYP4A11LMNAPKM | |
| SCHEMBL21438076 | 0.81 | NLRP3 (0.47) | SMN1; SMN2CYP4F2CYP4A11LMNAPKM | |
| SCHEMBL6366424 | 0.80 | LMNA (0.54) | SMN1; SMN2LMNAPKML3MBTL1KDM4E | |
| SCHEMBL31075841 | 0.78 | NLRP3 (0.47) | SMN1; SMN2CYP4F2CYP4A11LMNAPKM | |
| SCHEMBL31063021 | 0.78 | NLRP3 (0.47) | SMN1; SMN2CYP4F2CYP4A11LMNAPKM | |
| SCHEMBL26474562 | 0.77 | LMNA (0.46) | SMN1; SMN2LMNAPKML3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2566580-A1 | PROCESS FOR THE PREPARATION OF BIMOSIAMOSE | Revotar Biopharmaceuticals AG (DE) | 2013-03-13 | — | — | EP | disclosed |
| WO-2011138365-A1 | PROCESS FOR THE PREPARATION OF BIMOSIAMOSE | REVOTAR BIOPHARMACEUTICALS AG (DE) | 2011-11-10 | — | — | WO | disclosed |