Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2142618 | 0.83 | NPC1 (0.39) | L3MBTL1TDP1ALDH1A1MAPK1GSK3B | |
| SCHEMBL6400883 | 0.81 | NPC1 (0.39) | L3MBTL1TDP1ALDH1A1MAPK1MEN1 | |
| SCHEMBL11497084 | 0.79 | NPC1 (0.37) | L3MBTL1TDP1ALDH1A1MAPK1MEN1 | |
| SCHEMBL4621722 | 0.69 | NPC1 (0.40) | L3MBTL1ALDH1A1MAPK1GSK3BTRPA1 | |
| SCHEMBL10867266 | 0.68 | MMP9 (0.39) | L3MBTL1TDP1ALDH1A1MAPK1GSK3B | |
| SCHEMBL13623506 | 0.66 | ALDH1A1 (0.49) | L3MBTL1TDP1ALDH1A1MAPK1GSK3B | |
| SCHEMBL29061883 | 0.65 | — | — | |
| SCHEMBL3673842 | 0.65 | ALDH1A1 (0.38) | L3MBTL1TDP1ALDH1A1MAPK1GSK3B | |
| SCHEMBL864716 | 0.64 | MAPT (0.61) | L3MBTL1TDP1ALDH1A1MAPK1GSK3B | |
| SCHEMBL5799404 | 0.64 | ALDH1A1 (0.47) | L3MBTL1TDP1ALDH1A1MAPK1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8883935-B2 | High refractive index composition | BATTELLE MEMORIAL INSTITUTE (US) | 2014-11-11 | — | — | US | disclosed |
| EP-2563826-A2 | HIGH REFRACTIVE INDEX COMPOSITION | Battelle Memorial Institute (US) | 2013-03-06 | — | — | EP | disclosed |
| US-20130046054-A1 | HIGH REFRACTIVE INDEX COMPOSITION | BATTELLE MEMORIAL INSTITUTE (US) | 2013-02-21 | — | — | US | disclosed |
| WO-2011139856-A2 | HIGH REFRACTIVE INDEX COMPOSITION | BATTELLE MEMORIAL INSTITUTE (US) | 2011-11-10 | — | — | WO | disclosed |