SCHEMBL6400883

SCHEMBL6400883

COC1(OC)C=CC=CC1OCC(=O)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.39
RAB9A P51151 3/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
MAPT P10636 2/20 0.39
ALDH1A1 P00352 4/20 0.39
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.39
CYP1A2 P05177 2/20 0.39
CYP2C9 P11712 2/20 0.39
CYP2C19 P33261 1/20 0.39
L3MBTL1 Q9Y468 4/20 0.38
TDP1 Q9NUW8 3/20 0.38
LMNA P02545 2/20 0.37
POLB P06746 2/20 0.37
TSHR P16473 3/20 0.35
ALOX15 P16050 2/20 0.35
HSD17B10 Q99714 1/20 0.35
HPGD P15428 2/20 0.35
MAPK1 P28482 2/20 0.35
KDM4E B2RXH2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11497084 0.90 NPC1 (0.37) NPC1RAB9ASMN1; SMN2MAPTALDH1A1
SCHEMBL2142618 0.83 NPC1 (0.39) NPC1RAB9ASMN1; SMN2MAPTALDH1A1
SCHEMBL2593768 0.81 L3MBTL1 (0.39) NPC1RAB9ASMN1; SMN2MAPTALDH1A1
SCHEMBL501891 0.78 POLB (0.39) NPC1RAB9ASMN1; SMN2MAPTALDH1A1
SCHEMBL10867266 0.74 MMP9 (0.39) NPC1RAB9ASMN1; SMN2MAPTALDH1A1
SCHEMBL10959754 0.73 NPC1 (0.40) NPC1SMN1; SMN2MAPTALDH1A1KMT2A
SCHEMBL28380002 0.70 CES2 (0.39) NPC1RAB9ASMN1; SMN2MAPTALDH1A1
SCHEMBL28350465 0.69 TSHR (0.37) NPC1RAB9ASMN1; SMN2MAPTALDH1A1
SCHEMBL183220 0.69 KMT2A (0.39) NPC1RAB9ASMN1; SMN2MAPTALDH1A1
SCHEMBL28478305 0.68 CES2 (0.42) NPC1RAB9ASMN1; SMN2MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050142357-A1 High strength pressure sensitive adhesive ADHESIVES RESEARCH, INC. (US) 2005-06-30 US disclosed
WO-2004011568-A2 HIGH STRENGTH PRESSURE SENSITIVE ADHESIVE ADHESIVES RESEARCH, INC. (US) 2004-02-05 WO disclosed
US-6566466-B1 Reacting mixture of monomeric (meth)acrylic acid ester of a non- tertiary alcohol having from 1 to 30 carbon atoms, other monomer or polymer or graft macromer and liquid diluents under free radical polymerization condition ADHESIVES RESEARCH, INC. 2003-05-20 US disclosed
EP-0924276-A1 Two-step method for the production of pressure sensitive adhesive by radiation curing ADHESIVES RESEARCH, INC. (US) 1999-06-23 EP disclosed
US-5879759-A PROVIDING MACROMER AND SOLVENT-FREE RADIATION CURABLE COMPOSITION COMPRISED OF (METH)ACRYLIC ESTER OF NON-TERTIARY ALCOHOL, IRRADIATING TO FORM COATABLE SYRUP, MIXING WITH ADDITIONAL MONOMER, MULTIFUNCTIONAL MONOMER, IRRADIATING ADHESIVES RESEARCH, INC. (US) 1999-03-09 US disclosed
US-5670260-A BACKING CONTAINING URETHANE OLIGOMER ADHESIVES RESEARCH, INC. (US) 1997-09-23 US disclosed
EP-0003845-B1 ORTHOPEDIC DEVICES, MATERIALS AND METHODS UNION CARBIDE CORPORATION (US) 1983-08-31 EP disclosed
EP-0003741-B1 RADIATION CURABLE PRESSURE SENSITIVE ADHESIVE AND PROCESS OF PREPARATION THEREOF UNION CARBIDE CORPORATION (US) 1982-12-22 EP disclosed
EP-0003741-A2 Radiation curable pressure sensitive adhesive and process of preparation thereof UNION CARBIDE CORPORATION (US) 1979-09-05 EP disclosed
EP-0003845-A1 Orthopedic devices, materials and methods UNION CARBIDE CORPORATION (US) 1979-09-05 EP disclosed
US-4111769-A CARBAMYLOXYALKYL ACRYLATE, POLYOXYALKYLENE HOMO- OR COPOLYMER, PHOTOINIATOR UNION CARBIDE CORPORATION (US) 1978-09-05 US disclosed