Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | TACR3 | P29371 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 10/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13245865 | 0.86 | NOTUM (0.47) | NOTUMP2RX7TACR3DPP4DPP8 | |
| SCHEMBL24629903 | 0.82 | P2RX7 (0.47) | NOTUMP2RX7KCNH2TACR3POLB | |
| SCHEMBL25430234 | 0.81 | NOTUM (0.43) | NOTUMP2RX7TACR3DPP4DPP8 | |
| SCHEMBL17232814 | 0.80 | P2RX7 (0.48) | NOTUMP2RX7KCNH2TACR3POLB | |
| SCHEMBL16219061 | 0.76 | P2RX7 (0.45) | NOTUMP2RX7TACR3DPP4DPP8 | |
| SCHEMBL13223505 | 0.76 | PDK2 (0.49) | NOTUMP2RX7TACR3POLBDRD2 | |
| Trifluoroacetic Acid SCHEMBL25427998 | 0.75 | DPP4 (0.58) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL17509119 | 0.74 | DPP4 (0.53) | NOTUMP2RX7TACR3DPP4DPP8 | |
| SCHEMBL17509130 | 0.73 | NAAA (0.47) | NOTUMP2RX7TACR3DPP4DPP8 | |
| SCHEMBL10095021 | 0.73 | NR1H2 (0.47) | NOTUMP2RX7POLBDRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023144793-A1 | POL THETA INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2023-08-03 | — | — | WO | disclosed |