Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 2/20 | 0.38 |
| ▸ | FNTB | P49356 | 2/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | TACR3 | P29371 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25937808 | 0.85 | DPP4 (0.49) | SIGMAR1DPP4DPP8 | |
| SCHEMBL25430234 | 0.83 | NOTUM (0.43) | P2RX7DRD2DRD3NOTUMPDK2 | |
| SCHEMBL10095021 | 0.79 | NR1H2 (0.47) | ALDH1A1MEN1KMT2AP2RX7DRD2 | |
| SCHEMBL25937529 | 0.78 | SIGMAR1 (0.47) | ALDH1A1MEN1TSHRKMT2ASIGMAR1 | |
| SCHEMBL25937516 | 0.75 | SIGMAR1 (0.47) | ALDH1A1MEN1TSHRKMT2ASIGMAR1 | |
| SCHEMBL13245865 | 0.75 | NOTUM (0.47) | MEN1TSHRKMT2AP2RX7DRD2 | |
| SCHEMBL25937802 | 0.74 | NOTUM (0.46) | P2RX7DRD2DRD3NOTUMPDK2 | |
| SCHEMBL7919249 | 0.73 | DPP4 (0.58) | DPP4DPP8 | |
| SCHEMBL19981885 | 0.73 | ALDH1A1 (0.51) | ALDH1A1MEN1TSHRKMT2ASIGMAR1 | |
| SCHEMBL25313503 | 0.72 | ALDH1A1 (0.59) | ALDH1A1MEN1TSHRKMT2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023144793-A1 | POL THETA INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023144793-A1 | POL THETA INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2023-08-03 | — | — | WO | disclosed |