Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 4/20 | 0.41 |
| ▸ | FNTA | P49354 | 2/20 | 0.41 |
| ▸ | FNTB | P49356 | 2/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | MYT1 | Q01538 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | SPR | P35270 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5765341 | 0.80 | NR1H2 (0.49) | ALDH1A1NAMPTCDK1MYT1NR1H2 | |
| SCHEMBL25937529 | 0.79 | SIGMAR1 (0.47) | SIGMAR1ALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL25937516 | 0.77 | SIGMAR1 (0.47) | SIGMAR1ALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL25937815 | 0.73 | NAMPT (0.44) | SIGMAR1NAMPTCDK1MYT1SPR | |
| SCHEMBL19981885 | 0.72 | ALDH1A1 (0.51) | SIGMAR1ALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL25313503 | 0.71 | ALDH1A1 (0.59) | SIGMAR1ALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL5445038 | 0.71 | ALDH1A1 (0.59) | SIGMAR1ALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL28018778 | 0.71 | MEN1 (0.59) | SIGMAR1ALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL1306785 | 0.71 | SIGMAR1 (0.61) | SIGMAR1ALDH1A1FNTAFNTBCYP3A4 | |
| SCHEMBL1329658 | 0.71 | TSHR (0.62) | SIGMAR1ALDH1A1MEN1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023144793-A1 | POL THETA INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023144793-A1 | POL THETA INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2023-08-03 | — | — | WO | disclosed |