Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | FNTA | P49354 | 2/20 | 0.43 |
| ▸ | FNTB | P49356 | 2/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | VNN1 | O95497 | 1/20 | 0.41 |
| ▸ | SCD | O00767 | 1/20 | 0.40 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | MYT1 | Q01538 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 2/20 | 0.37 |
| ▸ | MMP13 | P45452 | 2/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25937529 | 0.81 | SIGMAR1 (0.47) | SIGMAR1ALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL25429882 | 0.81 | SCD (0.46) | ALDH1A1MEN1KMT2AP2RX7VNN1 | |
| SCHEMBL1018629 | 0.80 | P2RX7 (0.46) | ALDH1A1P2RX7VNN1SCDSCD5 | |
| SCHEMBL25937813 | 0.77 | SIGMAR1 (0.47) | SIGMAR1ALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL25937798 | 0.75 | ALDH1A1 (0.47) | SIGMAR1ALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL26967204 | 0.74 | NAMPT (0.34) | SIGMAR1P2RX7VNN1NAMPT | |
| SCHEMBL1083238 | 0.74 | SIGMAR1 (0.45) | SIGMAR1ALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL25937522 | 0.73 | SCD (0.46) | SIGMAR1P2RX7VNN1SCDSCD5 | |
| SCHEMBL25937808 | 0.73 | DPP4 (0.49) | SIGMAR1 | |
| SCHEMBL31377191 | 0.72 | P2RX7 (0.36) | ALDH1A1MEN1KMT2AP2RX7VNN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023144793-A1 | POL THETA INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023144793-A1 | POL THETA INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2023-08-03 | — | — | WO | disclosed |