Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGAM1 | P18669 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.36 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.36 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GNG2 | P59768 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL458284 | 0.79 | SMN1; SMN2 (0.48) | PGAM1NFKB1L3MBTL1KDM4AUSP2 | |
| SCHEMBL2592300 | 0.79 | PGAM1 (0.44) | PGAM1NFKB1L3MBTL1KDM4AUSP2 | |
| SCHEMBL8145542 | 0.77 | PGAM1 (0.42) | PGAM1NFKB1L3MBTL1KDM4AUSP2 | |
| SCHEMBL28837581 | 0.77 | SMN1; SMN2 (0.46) | PGAM1NFKB1L3MBTL1KDM4AUSP2 | |
| Water SCHEMBL3801022 | 0.76 | PGAM1 (0.41) | PGAM1NFKB1L3MBTL1KDM4AUSP2 | |
| SCHEMBL24631331 | 0.75 | TTR (0.47) | PGAM1TTRALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL9763220 | 0.74 | MAPT (0.52) | PGAM1NFKB1L3MBTL1KDM4AUSP2 | |
| SCHEMBL4875071 | 0.74 | PGAM1 (0.44) | PGAM1PLCG1TTRALDH1A1SMN1; SMN2 | |
| SCHEMBL29945057 | 0.74 | PGAM1 (0.44) | PGAM1PLCG1TTRALDH1A1SMN1; SMN2 | |
| SCHEMBL460174 | 0.73 | STAT3 (0.51) | PGAM1NFKB1L3MBTL1KDM4AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11740233-B2 | Antibody-nanoparticle conjugates and methods for making and using such conjugates | VENTANA MEDICAL SYSTEMS, INC. (US) | 2023-08-29 | — | — | US | disclosed |
| US-20180372733-A1 | ANTIBODY-NANOPARTICLE CONJUGATES AND METHODS FOR MAKING AND USING SUCH CONJUGATES | VENTANA MED SYST INC (US) | 2018-12-27 | — | — | US | disclosed |
| US-10031134-B2 | Antibody-nanoparticle conjugates and methods for making and using such conjugates | VENTANA MEDICAL SYSTEMS, INC. (US) | 2018-07-24 | — | — | US | disclosed |
| EP-2564203-B1 | ANTIBODY-NANOPARTICLE CONJUGATES AND METHODS FOR MAKING AND USING SUCH CONJUGATES | VENTANA MED SYST INC (US) | 2017-06-07 | — | — | EP | disclosed |
| US-20170131271-A1 | ANTIBODY-NANOPARTICLE CONJUGATES AND METHODS FOR MAKING AND USING SUCH CONJUGATES | VENTANA MEDICAL SYSTEMS, INC. | 2017-05-11 | — | — | US | disclosed |
| US-9442107-B2 | Antibody-nanoparticle conjugates and methods for making and using such conjugates | VENTANA MEDICAL SYSTEMS, INC. (US) | 2016-09-13 | — | — | US | disclosed |
| US-20160116462-A1 | ANTIBODY-NANOPARTICLE CONJUGATES AND METHODS FOR MAKING AND USING SUCH CONJUGATES | VENTANA MEDICAL SYSTEMS, INC. | 2016-04-28 | — | — | US | disclosed |
| US-9040310-B2 | Antibody-nanoparticle conjugates and methods for making and using such conjugates | VENTANA MEDICAL SYSTEMS, INC. (US) | 2015-05-26 | — | — | US | disclosed |
| EP-2564203-A2 | ANTIBODY-NANOPARTICLE CONJUGATES AND METHODS FOR MAKING AND USING SUCH CONJUGATES | Ventana Medical Systems, Inc. (US) | 2013-03-06 | — | — | EP | disclosed |
| US-20130034854-A1 | Antibody-Nanoparticle Conjugates and Methods for Making and Using Such Conjugates | VENTANA MEDICAL SYSTEMS, INC. (US) | 2013-02-07 | — | — | US | disclosed |
| WO-2011139792-A2 | ANTIBODY-NANOPARTICLE CONJUGATES AND METHODS FOR MAKING AND USING SUCH CONJUGATES | VENTANA MEDICAL SYSTEMS, INC. (US) | 2011-11-10 | — | — | WO | disclosed |