SCHEMBL460174

SCHEMBL460174

O=S(=O)(O)c1ccccc1-c1c(O)cccc1S(=O)(=O)O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STAT3 P40763 1/20 0.51
MAPT P10636 6/20 0.50
KMT2A Q03164 5/20 0.50
MEN1 O00255 4/20 0.50
MAOA P21397 3/20 0.50
PGAM1 P18669 1/20 0.49
HPGD P15428 4/20 0.48
TDP1 Q9NUW8 4/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
ALDH1A1 P00352 3/20 0.48
ALOX15 P16050 3/20 0.48
MAPK1 P28482 3/20 0.48
HSD17B10 Q99714 3/20 0.48
LMNA P02545 1/20 0.48
TSHR P16473 1/20 0.48
MAOB P27338 1/20 0.48
HTT P42858 1/20 0.48
POLB P06746 3/20 0.46
BLM P54132 3/20 0.46
MCL1 Q07820 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27279359 0.92 STAT3 (0.51) STAT3MAPTKMT2AMEN1MAOA
SCHEMBL30394362 0.92 STAT3 (0.51) STAT3MAPTKMT2AMEN1MAOA
SCHEMBL7868085 0.86 STAT3 (0.50) STAT3MAPTKMT2AMEN1MAOA
SCHEMBL13239519 0.83 STAT3 (0.74) STAT3MAPTKMT2AMEN1MAOA
SCHEMBL6155652 0.82 PGAM1 (0.44) STAT3MAPTKMT2AMEN1MAOA
SCHEMBL29700277 0.82 PGAM1 (0.44) STAT3MAPTKMT2AMEN1MAOA
SCHEMBL4163086 0.81 NFKB1 (0.45) STAT3MAPTKMT2AMEN1MAOA
SCHEMBL7864030 0.81 BACE1 (0.44) STAT3MAPTKMT2AMEN1MAOA
SCHEMBL27725565 0.80 STAT3 (0.60) STAT3MAPTKMT2AMEN1MAOA
SCHEMBL27662691 0.79 MEN1 (0.70) STAT3MAPTKMT2AMEN1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060193789-A1 Surfacant, film forming agent, water, gas propellant; plant and animal extracts and oils; may include malathion FOAMIX LTD. (IL) 2006-08-31 US claimed
US-20240099948-A1 Compositions Comprising Silicon Dioxide-Based Particles Including One or More Agents COLABS INT'L CORP. (US) 2024-03-28 US disclosed
US-11839674-B2 Compositions comprising silicon dioxide-based particles including one or more agents CoLabs International Corporation (US) 2023-12-12 US disclosed
US-11752086-B2 Topical formulations and methods MYOCEPT INC. (US) 2023-09-12 US disclosed
US-11724134-B2 Compositions containing a cellulose derived capsule with a sunscreen active agent CoLabs International Corporation (US) 2023-08-15 US disclosed
EP-3813786-A1 COMPOSITIONS COMPRISING SILICON DIOXIDE-BASED PARTICLES INCLUDING ONE OR MORE AGENTS Colabs International Corporation (US) 2021-05-05 EP disclosed
US-10889753-B2 Self-breakable treatment fluids for use in subterranean formation operations HALLIBURTON ENERGY SERVICES, INC. (US) 2021-01-12 US disclosed
US-20190290940-A1 Compositions Containing a Cellulose Derived Capsule with a Sunscreen Active Agent CoLabs International Corporation (US) 2019-09-26 US disclosed
US-10322301-B2 Compositions containing a cellulose derived capsule with a sunscreen active agent CoLabs International Corporation (US) 2019-06-18 US disclosed
US-20190127629-A1 SELF-BREAKABLE TREATMENT FLUIDS FOR USE IN SUBTERRANEAN FORMATION OPERATIONS HALLIBURTON ENERGY SERVICES, INC. 2019-05-02 US disclosed
US-20060093636-A1 Comprises allantoin and at least one anionic or nonionic emulsifier that is substantially hydrophilic and is soluble in water; composition is in the form of an oil-in-water emulsion; pH of the composition is about 3.0 to 6.0; preferred acidic anionic polymer is a carboxypolymethylene polymer; stability ALWYN COMPANY, INC. (US) 2006-05-04 US disclosed
US-20060067959-A1 Compositions and methods for treatment of solar damage NIMNI MARCEL 2006-03-30 US disclosed
US-20060045926-A1 Methods and compositions for enhancing collagen and proteoglycan synthesis in the skin NIMNI MARCEL 2006-03-02 US disclosed
WO-2003070161-A2 EMULSIFIED SKIN CARE COMPOSITION CONTAINING SALICYLIC ACID, LANOLIN OIL, AND PROPYLENE GLYCOL ALWYN COMPANY, INC. (US) 2003-08-28 WO disclosed
US-20030157137-A1 Emulsified skin care composition containing salicylic acid, lanolin oil, and propylene glycol ALWYN COMPANY, INC. 2003-08-21 US disclosed
US-20030147968-A1 Allantoin-containing preparations for administration as gels and aerosols ALWYN COMPANY, INC. 2003-08-07 US disclosed
WO-2003053369-A1 ALLANTOIN-CONTAINING PREPARATIONS FOR ADMINISTRATION AS GELS AND AEROSOLS ALWYN COMPANY, INC. (US) 2003-07-03 WO disclosed
US-20020054895-A1 And at least one anionic or nonionic emulsifier that is substantially hydrophilic and is soluble in water; skin protectants ALWYN COMPANY, INC. 2002-05-09 US disclosed
US-6376557-B1 TRANSDERMAL SUPPLYING ZAVERI CHANDA BHUWALKA (US) 2002-04-23 US disclosed
WO-2001068107-A1 HAIR RESTORATION FORMULATION ZAVERI CHANDA BHUWALKA (US) 2001-09-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11724134-B2 Compositions containing a cellulose derived capsule with a sunscreen active agent CUTA, ACMSD, TYR STAT3 3774/4885MAPT 264/4885KMT2A 4008/4885
US-20060045926-A1 Methods and compositions for enhancing collagen and proteoglycan synthesis in the skin COL1A1, COL14A1, COL2A1 STAT3 329/4885MAPT 3935/4885KMT2A 4493/4885
US-20190290940-A1 Compositions Containing a Cellulose Derived Capsule with a Sunscreen Active Agent CUTA, ACMSD, TYR STAT3 3774/4885MAPT 264/4885KMT2A 4008/4885
US-11752086-B2 Topical formulations and methods KRT18, ANXA3, VIP STAT3 3238/4885MAPT 1510/4885KMT2A 4640/4885
US-10322301-B2 Compositions containing a cellulose derived capsule with a sunscreen active agent CUTA, ACMSD, TYR STAT3 3774/4885MAPT 264/4885KMT2A 4008/4885
US-20240099948-A1 Compositions Comprising Silicon Dioxide-Based Particles Including One or More Agents MSN, LIPE, CUTA STAT3 2060/4885MAPT 1241/4885KMT2A 2603/4885
US-11839674-B2 Compositions comprising silicon dioxide-based particles including one or more agents MSN, LIPE, CUTA STAT3 2081/4885MAPT 1190/4885KMT2A 2641/4885
US-20060067959-A1 Compositions and methods for treatment of solar damage AAAS, LRRK2, CSTB STAT3 619/4885MAPT 119/4885KMT2A 2179/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.