Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 7/20 | 1.00 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.69 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.69 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.69 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.68 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.68 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.68 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.68 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.68 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.68 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | HTR6 | P50406 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14258738 | 0.89 | ACHE (0.80) | ACHEAKR1B1HDAC1HDAC6GRIN1 | |
| SCHEMBL11183259 | 0.86 | ACHE (0.76) | ACHEAKR1B1HTR6 | |
| SCHEMBL11186197 | 0.85 | ACHE (0.74) | ACHEAKR1B1HDAC1HDAC6HTR6 | |
| SCHEMBL8359525 | 0.85 | ACHE (0.73) | ACHEAKR1B1HDAC1HDAC6GRIN1 | |
| SCHEMBL11208411 | 0.85 | ACHE (1.00) | ACHEAKR1B1HDAC1HDAC6 | |
| SCHEMBL633048 | 0.84 | ACHE (1.00) | ACHEAKR1B1HDAC1HDAC6 | |
| Hydrochloric Acid SCHEMBL7137005 | 0.84 | ACHE (0.98) | ACHEAKR1B1HDAC1HDAC6 | |
| SCHEMBL2188030 | 0.83 | ACHE (0.76) | ACHEHDAC1HDAC6GRIN1GRIN2A | |
| SCHEMBL60976 | 0.82 | AKR1B1 (0.74) | ACHEAKR1B1HDAC1HDAC6HTR6 | |
| SCHEMBL4892784 | 0.82 | ACHE (0.80) | ACHEAKR1B1HDAC1HDAC6HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011139242-A2 | PROCESS FOR THE PREPARATION OF 2,3,4,5-TETRAHYDRO-1H-PYRIDO[4,3-B]INDOLE DERIVATIVES | USTAV EXPIREMENTÁLNEJ FARMAKOLÓGIE A TOXIKOLÓGIE SAV (SK) | 2011-11-10 | — | — | WO | disclosed |
| US-20110046368-A1 | LIGANDS OF 5-HT6 RECEPTORS, A PHARMACEUTICAL COMPOSITION, METHOD FOR THE PRODUCTION AND USE THEREOF | IVASHCHENKO ANDREY ALEXANDROVICH | 2011-02-24 | — | — | US | disclosed |
| US-20110046368-A1 | LIGANDS OF 5-HT6 RECEPTORS, A PHARMACEUTICAL COMPOSITION, METHOD FOR THE PRODUCTION AND USE THEREOF | IVASHCHENKO ANDREY ALEXANDROVICH | 2011-02-24 | — | — | US | disclosed |
| EP-2184064-A2 | LIGANDS OF 5-HT6 RECEPTORS, A PHARMACEUTICAL COMPOSITION, METHOD FOR THE PRODUCTION AND USE THEREOF | Alla Chem, LLC. (US) | 2010-05-12 | — | — | EP | disclosed |
| WO-2008060190-A2 | LIGANDS OF 5-HT6 RECEPTORS, A PHARMACEUTICAL COMPOSITION, METHOD FOR THE PRODUCTION AND USE THEREOF | ALLA CHEM, LLC (US) | 2008-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110046368-A1 | LIGANDS OF 5-HT6 RECEPTORS, A PHARMACEUTICAL COMPOSITION, METHOD FOR THE PRODUCTION AND USE THEREOF | HTR6, HTR1A, HTR3B | ACHE 530/4885AKR1B1 1901/4885HDAC1 2402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.