Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23432350 | 0.77 | EGFR (0.40) | EGFRAPP | |
| SCHEMBL27421633 | 0.76 | ALDH1A1 (0.34) | — | |
| SCHEMBL28559337 | 0.76 | SORT1 (0.32) | — | |
| SCHEMBL25940821 | 0.74 | CASP1 (0.33) | — | |
| SCHEMBL11132613 | 0.73 | EGFR (0.38) | EGFRAPP | |
| SCHEMBL25938941 | 0.71 | APP (0.37) | EGFRAPP | |
| SCHEMBL38659324 | 0.70 | HDAC1 (0.37) | — | |
| SCHEMBL23428954 | 0.70 | EGFR (0.36) | EGFRAPP | |
| SCHEMBL14294037 | 0.70 | SNCA (0.31) | APP | |
| SCHEMBL21020940 | 0.69 | EGFR (0.34) | EGFRAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3820574-B1 | 3-(5-AMINO-1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES AND THEIR USE IN THE TREATMENT OF IKAROS FAMILY ZINC FINGER 2 (IKZF2)-DEPENDENT DISEASES | NOVARTIS AG (CH) | 2023-08-09 | — | — | EP | disclosed |