SCHEMBL259402

SCHEMBL259402

Cc1cc(C)c(Oc2nc(Cl)nc(OCC3CO3)n2)c(C)c1

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.39
ALDH1A1 P00352 3/20 0.36
GLA P06280 1/20 0.36
TP53 P04637 3/20 0.35
TSHR P16473 3/20 0.35
HIF1A Q16665 2/20 0.35
CYP3A4 P08684 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
TDP1 Q9NUW8 1/20 0.33
MAPT P10636 2/20 0.32
HPGD P15428 2/20 0.32
MEN1 O00255 1/20 0.32
CYP1A2 P05177 1/20 0.32
KMT2A Q03164 1/20 0.32
PPARG P37231 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9073833 0.87 HSP90AA1 (0.55) HSP90AA1ALDH1A1GLATP53TSHR
SCHEMBL4327960 0.84 ALDH1A1 (0.38) ALDH1A1GLATP53TSHRHIF1A
SCHEMBL9064088 0.84 ALDH1A1 (0.40) ALDH1A1GLATP53TSHRHIF1A
SCHEMBL4319812 0.82 HSP90AA1 (0.32) HSP90AA1
SCHEMBL48796 0.81 TDP1 (0.41) ALDH1A1GLATP53TSHRHIF1A
SCHEMBL49211 0.81 HSP90AA1 (0.53) HSP90AA1ALDH1A1SMN1; SMN2MAPTMEN1
SCHEMBL49631 0.81 HSP90AA1 (0.46) HSP90AA1ALDH1A1KMT2A
SCHEMBL9188392 0.80 HSP90AA1 (0.44) HSP90AA1MAPTMEN1KMT2A
SCHEMBL9013225 0.79 KMT2A (0.40) ALDH1A1GLATP53TSHRHIF1A
SCHEMBL9284410 0.78 ALDH1A1 (0.58) HSP90AA1ALDH1A1GLATP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0550210-B1 Polyphenylene ether/polyamide compositions GEN ELECTRIC (US) 1997-03-19 EP claimed
EP-0522767-B1 Method for preparing reactive triazine-capped aromatic polymers GEN ELECTRIC (US) 1996-12-18 EP claimed
US-5324796-A Improved tensile elongation and strength, chloroccyanurate derivative GENERAL ELECTRIC COMPANY (US) 1994-06-28 US claimed
EP-0601781-A2 Polyarylene sulfide and epoxy-functionalized siloxane blends GENERAL ELECTRIC COMPANY (US) 1994-06-15 EP claimed
US-5264496-A Aromatic hydroxy group polymer modified with chlorotriazines and using phase transfer catalyst and tertiary amine for reaction GENERAL ELECTRIC COMPANY (US) 1993-11-23 US claimed
EP-0550210-A1 Polyphenylene ether/polyamide compositions GENERAL ELECTRIC COMPANY (US) 1993-07-07 EP claimed
EP-0550206-A2 Polyphenylene ether/polyamide compositions GENERAL ELECTRIC COMPANY (US) 1993-07-07 EP claimed
EP-0522767-A2 Method for preparing reactive triazine-capped aromatic polymers GENERAL ELECTRIC COMPANY (US) 1993-01-13 EP claimed
EP-0501155-A2 Process for functionalizing polyphenylene ether GENERAL ELECTRIC COMPANY (US) 1992-09-02 EP claimed
US-5115043-A Endcapping GENERAL ELECTRIC COMPANY (US) 1992-05-19 US claimed
EP-1423372-B1 TRIAZINE COMPOUNDS, POLYMERS COMPRISING TRIAZINE STRUCTURAL UNITS, AND PROCESSES FOR THE PREPARATION OF THESE POLYMERS SABIC GLOBAL TECHNOLOGIES BV (NL) 2016-07-20 EP disclosed
US-8133844-B2 Heat-sensitive transfer image-receiving sheet FUJIFILM CORPORATION (JP) 2012-03-13 US disclosed
US-8124563-B2 Heat-sensitive transfer image-receiving sheet FUJIFILM CORPORATION (JP) 2012-02-28 US disclosed
US-7981837-B2 Heat-sensitive transfer image-receiving sheet FUJIFILM CORPORATION (JP) 2011-07-19 US disclosed
US-7968496-B2 Heat-sensitive transfer image-receiving sheet, image forming method using heat-sensitive transfer system and method of producing heat-sensitive transfer image receiving sheet FUJIFILM CORPORATION (JP) 2011-06-28 US disclosed
US-4895945-A Epoxidized chlorotriazine compounds GENERAL ELECTRIC COMPANY (US) 1990-01-23 US disclosed
EP-0349717-A2 Polyphenylene ether-polyester copolymers from epoxytriazine-capped polyphenylene ethers GENERAL ELECTRIC COMPANY (US) 1990-01-10 EP disclosed
EP-0347539-A2 Epoxytriazine-capped polyphenylene ethers and method for their preparation GENERAL ELECTRIC COMPANY (US) 1989-12-27 EP disclosed
EP-0347827-A2 Epoxytriazine-capped polyphenylene ethers and method of preparation GENERAL ELECTRIC COMPANY (US) 1989-12-27 EP disclosed
EP-0347828-A2 Compositions comprising polyphenylene ether-polyester copolymers from epoxytriazine-capped polyphenylene ethers GENERAL ELECTRIC COMPANY (US) 1989-12-27 EP disclosed