Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | VDR | P11473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 4/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.31 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9013436 | 0.81 | KMT2A (0.50) | KMT2ALMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL259402 | 0.79 | HSP90AA1 (0.39) | KMT2AMAPTALDH1A1GLASMN1; SMN2 | |
| SCHEMBL48796 | 0.76 | TDP1 (0.41) | KMT2ALMNAMAPTALDH1A1GLA | |
| SCHEMBL9064088 | 0.74 | ALDH1A1 (0.40) | KMT2ALMNAMAPTVDRALDH1A1 | |
| SCHEMBL4308247 | 0.73 | TDP1 (0.41) | KMT2ALMNAMAPTALDH1A1GLA | |
| SCHEMBL9174762 | 0.72 | ALDH1A1 (0.40) | KMT2ALMNAMAPTALDH1A1GLA | |
| SCHEMBL31398434 | 0.72 | ALDH1A1 (0.45) | MAPTALDH1A1SMN1; SMN2TP53CYP3A4 | |
| SCHEMBL49542 | 0.71 | SMN1; SMN2 (0.47) | KMT2ALMNAMAPTALDH1A1GLA | |
| SCHEMBL5608545 | 0.70 | KMT2A (0.34) | KMT2A | |
| SCHEMBL9073833 | 0.69 | HSP90AA1 (0.55) | KMT2ALMNAMAPTALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563266-A | Method of use of disubstituted monochlorotriazines | GENERAL ELECTRIC COMPANY (US) | 1996-10-08 | — | — | US | disclosed |
| US-5563266-A | Method of use of disubstituted monochlorotriazines | GENERAL ELECTRIC COMPANY (US) | 1996-10-08 | — | — | US | disclosed |
| US-5446155-A | Reacting monoorganoxy dichloro-triazine with monohydroxy aliphatic compound in non-polar solvent and aqueous alkali metal hydroxide solution with the presence of phase transfer catalysts | GENERAL ELECTRIC COMPANY (US) | 1995-08-29 | — | — | US | disclosed |
| US-5446155-A | Reacting monoorganoxy dichloro-triazine with monohydroxy aliphatic compound in non-polar solvent and aqueous alkali metal hydroxide solution with the presence of phase transfer catalysts | GENERAL ELECTRIC COMPANY (US) | 1995-08-29 | — | — | US | disclosed |
| US-5312918-A | Method for preparing substituted nitrogen-heterocyclic compounds | GENERAL ELECTRIC COMPANY (US) | 1994-05-17 | — | — | US | disclosed |
| EP-0592143-A1 | Method for preparing disubstituted monochlorotriazines | GENERAL ELECTRIC COMPANY (US) | 1994-04-13 | — | — | EP | disclosed |
| EP-0592143-A1 | Method for preparing disubstituted monochlorotriazines | GENERAL ELECTRIC COMPANY (US) | 1994-04-13 | — | — | EP | disclosed |
| EP-0588524-A1 | Method for preparing substituted dichlorotriazines | GENERAL ELECTRIC COMPANY (US) | 1994-03-23 | — | — | EP | disclosed |
| US-5229513-A | Cyanuric chloride and phenolic compound | GENERAL ELECTRIC COMPANY (US) | 1993-07-20 | — | — | US | disclosed |
| EP-0513327-A1 | METHOD FOR PREPARING SUBSTITUTED NITROGEN-HETEROCYCLIC COMPOUNDS | GENERAL ELECTRIC COMPANY (US) | 1992-11-19 | — | — | EP | disclosed |
| WO-1992009601-A1 | METHOD FOR PREPARING SUBSTITUTED NITROGEN-HETEROCYCLIC COMPOUNDS | GENERAL ELECTRIC COMPANY (US) | 1992-06-11 | — | — | WO | disclosed |