Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25941248 | 0.90 | SMN1; SMN2 (0.40) | ALOX5SMN1; SMN2MAPTHSD17B10ALDH1A1 | |
| SCHEMBL25940696 | 0.85 | SMN1; SMN2 (0.53) | SMN1; SMN2MAPTHSD17B10ALDH1A1ATM | |
| SCHEMBL25941344 | 0.84 | PDE4B (0.39) | ALOX5SMN1; SMN2MAPTHSD17B10ALDH1A1 | |
| SCHEMBL25938395 | 0.83 | SMN1; SMN2 (0.40) | ALOX5SMN1; SMN2MAPTHSD17B10ALDH1A1 | |
| SCHEMBL25948520 | 0.83 | MAPT (0.40) | ALOX5SMN1; SMN2MAPTHSD17B10ALDH1A1 | |
| SCHEMBL25941252 | 0.79 | SMN1; SMN2 (0.42) | ALOX5SMN1; SMN2MAPTHSD17B10ALDH1A1 | |
| SCHEMBL25940661 | 0.77 | ELANE (0.46) | ALOX5ALDH1A1KMT2AKDM4ELMNA | |
| SCHEMBL26184766 | 0.77 | SMN1; SMN2 (0.39) | ALOX5SMN1; SMN2MAPTHSD17B10ALDH1A1 | |
| SCHEMBL25941246 | 0.75 | SMN1; SMN2 (0.50) | SMN1; SMN2MAPTHSD17B10ALDH1A1ATM | |
| SCHEMBL25942293 | 0.74 | MTNR1A (0.43) | SMN1; SMN2DPP4HPGDPOLBPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4209492-A1 | COMPOUND FOR TREATING THROMBOTIC DISEASES | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2023-07-12 | — | — | EP | disclosed |