Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25941246 | 0.89 | SMN1; SMN2 (0.50) | SMN1; SMN2HSD17B10ALDH1A1POLBATM | |
| SCHEMBL25940711 | 0.85 | ALOX5 (0.44) | SMN1; SMN2HSD17B10ALDH1A1POLBATM | |
| SCHEMBL25941342 | 0.84 | HSD17B10 (0.49) | SMN1; SMN2HSD17B10ALDH1A1POLBHPGD | |
| SCHEMBL25941343 | 0.83 | SMN1; SMN2 (0.47) | SMN1; SMN2HSD17B10ALDH1A1POLBHPGD | |
| SCHEMBL25938395 | 0.80 | SMN1; SMN2 (0.40) | SMN1; SMN2HSD17B10ALDH1A1POLBATM | |
| SCHEMBL25948520 | 0.80 | MAPT (0.40) | SMN1; SMN2HSD17B10ALDH1A1POLBATM | |
| SCHEMBL9557007 | 0.76 | SMN1; SMN2 (0.76) | SMN1; SMN2HSD17B10ALDH1A1POLBATM | |
| SCHEMBL30875172 | 0.76 | SMN1; SMN2 (0.76) | SMN1; SMN2HSD17B10ALDH1A1POLBATM | |
| SCHEMBL16377046 | 0.76 | KMT2A (0.48) | SMN1; SMN2HSD17B10ALDH1A1POLBHPGD | |
| SCHEMBL25941252 | 0.76 | SMN1; SMN2 (0.42) | SMN1; SMN2HSD17B10ALDH1A1POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4209492-A1 | COMPOUND FOR TREATING THROMBOTIC DISEASES | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2023-07-12 | — | — | EP | disclosed |