Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | P4HB | P07237 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25949325 | 0.86 | PDE4B (0.37) | MAPTSMN1; SMN2GAAKDM4EALDH1A1 | |
| SCHEMBL25938395 | 0.86 | SMN1; SMN2 (0.40) | MAPTSMN1; SMN2GAAHPGDKDM4E | |
| SCHEMBL25940711 | 0.83 | ALOX5 (0.44) | MAPTSMN1; SMN2GAAHPGDKDM4E | |
| SCHEMBL25940696 | 0.80 | SMN1; SMN2 (0.53) | MAPTSMN1; SMN2GAAHPGDKDM4E | |
| SCHEMBL26184766 | 0.78 | SMN1; SMN2 (0.39) | MAPTSMN1; SMN2GAAHPGDKDM4E | |
| SCHEMBL25941254 | 0.77 | SMN1; SMN2 (0.38) | MAPTSMN1; SMN2GAAHPGDKDM4E | |
| SCHEMBL25941248 | 0.74 | SMN1; SMN2 (0.40) | MAPTSMN1; SMN2GAAHPGDKDM4E | |
| SCHEMBL25948787 | 0.74 | MTNR1A (0.43) | SMN1; SMN2HPGDKDM4EPDE4BPOLB | |
| SCHEMBL25938744 | 0.73 | MTNR1A (0.43) | SMN1; SMN2KDM4EPDE4BPOLBMTNR1A | |
| SCHEMBL25949367 | 0.73 | KDM4E (0.53) | SMN1; SMN2GAAHPGDKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4209492-A1 | COMPOUND FOR TREATING THROMBOTIC DISEASES | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2023-07-12 | — | — | EP | disclosed |