Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 14/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 6/20 | 0.41 |
| ▸ | TGFB2 | P61812 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25942360 | 0.80 | TGFBR1 (0.46) | IRAK4TGFBR1TGFB2 | |
| SCHEMBL25942364 | 0.78 | TGFBR1 (0.57) | IRAK4TGFBR1 | |
| SCHEMBL25334386 | 0.77 | TGFBR1 (0.55) | IRAK4TGFBR1 | |
| SCHEMBL25942424 | 0.76 | TGFBR1 (0.44) | IRAK4TGFBR1 | |
| SCHEMBL25942361 | 0.75 | TRPA1 (0.51) | IRAK4TGFBR1 | |
| SCHEMBL25942310 | 0.74 | TGFBR1 (0.49) | IRAK4TGFBR1 | |
| SCHEMBL29501083 | 0.74 | TGFBR1 (0.38) | IRAK4TGFBR1 | |
| SCHEMBL25942605 | 0.74 | TGFBR1 (0.55) | IRAK4TGFBR1 | |
| SCHEMBL25942249 | 0.73 | TGFBR1 (0.46) | IRAK4TGFBR1 | |
| SCHEMBL25942304 | 0.73 | TGFBR1 (0.57) | IRAK4TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230303562-A1 | PYRAZOLE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-09-28 | — | — | US | disclosed |
| US-20230303562-A1 | PYRAZOLE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-09-28 | — | — | US | disclosed |
| EP-4219453-A1 | PYRAZOLE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) | 2023-08-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230303562-A1 | PYRAZOLE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | CYP51A1, CYP4F11, WEE1 | IRAK4 1996/4885TGFBR1 1681/4885TGFB2 423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.