Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | TAF1 | P21675 | 1/20 | 0.39 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | KDM6A | O15550 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20516739 | 0.79 | BRD4 (0.38) | BRD9BRD4TAF1BRPF1CREBBP | |
| SCHEMBL29911927 | 0.79 | BRD9 (0.38) | BRD9BRD4TAF1BRPF1CREBBP | |
| SCHEMBL15717311 | 0.77 | BRD9 (0.37) | BRD9BRD4TAF1BRPF1CREBBP | |
| SCHEMBL25344358 | 0.77 | BRD9 (0.37) | BRD9BRD4TAF1BRPF1CREBBP | |
| SCHEMBL19785547 | 0.77 | BRD9 (0.37) | BRD9BRD4TAF1BRPF1CREBBP | |
| SCHEMBL31439950 | 0.77 | ATAD2 (0.39) | BRD9BRD4TAF1BRPF1CREBBP | |
| SCHEMBL21957151 | 0.74 | MAPT (0.56) | BRD9BRD4TAF1BRPF1CREBBP | |
| SCHEMBL28956221 | 0.74 | TRIM24 (0.36) | BRD9BRD4TAF1BRPF1CREBBP | |
| SCHEMBL22990507 | 0.73 | BRD4 (0.34) | BRD9BRD4TAF1BRPF1CREBBP | |
| SCHEMBL25331540 | 0.73 | LMNA (0.59) | BRD9BRD4TAF1BRPF1CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117295730-A | Process for preparing BTK inhibitor | 豪夫迈·罗氏有限公司 | 2023-12-26 | — | — | CN | disclosed |
| EP-2566869-A1 | PYRIDONE AND AZA-PYRIDONE COMPOUNDS AND METHODS OF USE | Gilead Connecticut, Inc. (US) | 2013-03-13 | — | — | EP | disclosed |
| WO-2011140488-A1 | PYRIDONE AND AZA-PYRIDONE COMPOUNDS AND METHODS OF USE | GILEAD CONNECTICUT, INC. (US) | 2011-11-10 | — | — | WO | disclosed |