Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 10/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25945248 | 0.94 | PKM (0.48) | PKMALOX5MEN1KMT2AKDM4E | |
| SCHEMBL25944007 | 0.90 | ALOX5 (0.45) | PKMALOX5MEN1KMT2AKDM4E | |
| SCHEMBL25944786 | 0.88 | ALOX5 (0.43) | PKMALOX5MEN1KMT2AKDM4E | |
| SCHEMBL25949559 | 0.87 | ALOX5 (0.44) | PKMALOX5MEN1KMT2AKDM4E | |
| SCHEMBL25945511 | 0.86 | PKM (0.46) | PKMALOX5MEN1KMT2AKDM4E | |
| SCHEMBL25939175 | 0.86 | PKM (0.45) | PKMALOX5MEN1KMT2AKDM4E | |
| SCHEMBL25949271 | 0.85 | PKM (0.46) | PKMALOX5MEN1KMT2AKDM4E | |
| SCHEMBL25944857 | 0.84 | ALOX5 (0.48) | PKMALOX5MEN1KMT2AKDM4E | |
| SCHEMBL25945344 | 0.83 | ALOX5 (0.42) | PKMALOX5MEN1KMT2AKDM4E | |
| SCHEMBL25946014 | 0.83 | ALOX5 (0.44) | PKMALOX5MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4209492-A1 | COMPOUND FOR TREATING THROMBOTIC DISEASES | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2023-07-12 | — | — | EP | disclosed |