SCHEMBL25946014 — predicted protein targets

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	ALOX5	P09917	9/20	0.44

▸	KDM4E	B2RXH2	3/20	0.42

▸	PKM	P14618	1/20	0.41

▸	ALDH1A1	P00352	2/20	0.40

▸	MEN1	O00255	2/20	0.40

▸	KMT2A	Q03164	2/20	0.40

▸	GAA	P10253	1/20	0.40

▸	HPGD	P15428	1/20	0.40

▸	ELANE	P08246	2/20	0.39

▸	PRKCZ	Q05513	1/20	0.39

▸	GABRA2	P47869	1/20	0.38

▸	GABRB2	P47870	1/20	0.38

▸	TSHR	P16473	1/20	0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL25945511	0.91	PKM (0.46)	ALOX5KDM4EPKMALDH1A1MEN1
SCHEMBL25944494	0.90	KDM4E (0.46)	ALOX5KDM4EPKMALDH1A1MEN1
SCHEMBL25949559	0.90	ALOX5 (0.44)	ALOX5KDM4EPKMALDH1A1MEN1
SCHEMBL25948781	0.89	ALOX5 (0.43)	ALOX5KDM4EPKMALDH1A1MEN1
SCHEMBL25945248	0.87	PKM (0.48)	ALOX5KDM4EPKMALDH1A1MEN1
SCHEMBL25939466	0.87	ALOX5 (0.40)	ALOX5KDM4EPKMALDH1A1MEN1
SCHEMBL25944857	0.83	ALOX5 (0.48)	ALOX5KDM4EPKMALDH1A1MEN1
SCHEMBL25944221	0.83	PKM (0.50)	ALOX5KDM4EPKMALDH1A1MEN1
SCHEMBL25945344	0.83	ALOX5 (0.42)	ALOX5KDM4EPKMALDH1A1MEN1
SCHEMBL25945766	0.83	ALOX5 (0.46)	ALOX5KDM4EPKMALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4209492-A1	COMPOUND FOR TREATING THROMBOTIC DISEASES	Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN)	2023-07-12	—	—	EP	disclosed