Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | SMAD3 | P84022 | 2/20 | 0.41 |
| ▸ | APAF1 | O14727 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25944378 | 0.89 | ATM (0.46) | ATMSMN1; SMN2ALDH1A1KDM1ASMAD3 | |
| SCHEMBL25944377 | 0.85 | ATM (0.61) | ATMSMN1; SMN2ALDH1A1KDM1ASMAD3 | |
| SCHEMBL25942412 | 0.84 | TSHR (0.48) | SMN1; SMN2ALDH1A1KDM1ASMAD3APAF1 | |
| SCHEMBL25944380 | 0.83 | ATM (0.41) | ATMSMN1; SMN2ALDH1A1KDM1ASMAD3 | |
| SCHEMBL25944383 | 0.80 | AAK1 (0.39) | ATMSMN1; SMN2ALDH1A1KDM1ASMAD3 | |
| SCHEMBL25944690 | 0.80 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1LMNAELANEKDM4E | |
| SCHEMBL25941571 | 0.77 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1LMNAELANEKDM4E | |
| SCHEMBL30633775 | 0.76 | LMNA (0.47) | ATMSMN1; SMN2ALDH1A1KDM1ASMAD3 | |
| SCHEMBL26613924 | 0.76 | LMNA (0.47) | ATMSMN1; SMN2ALDH1A1KDM1ASMAD3 | |
| SCHEMBL29429161 | 0.76 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1KDM1ASMAD3APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4209492-A1 | COMPOUND FOR TREATING THROMBOTIC DISEASES | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2023-07-12 | — | — | EP | disclosed |