SCHEMBL25944609

SCHEMBL25944609

Cc1cccc2c3cc(-n4c5ccccc5c5cc(-c6ccc7c(c6)c6ccccc6n7-c6ccccc6)ccc54)ccc3n(-c3ccccc3)c12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
ATM Q13315 1/20 0.47
ALKBH5 Q6P6C2 1/20 0.44
FTO Q9C0B1 1/20 0.44
PTGER4 P35408 1/20 0.38
TSPO P30536 1/20 0.35
HDAC4 P56524 1/20 0.35
GAA P10253 2/20 0.34
ALDH1A1 P00352 2/20 0.34
LMNA P02545 2/20 0.34
RAC2 P15153 1/20 0.34
RAC3 P60763 1/20 0.34
CDC42 P60953 1/20 0.34
RAC1 P63000 1/20 0.34
NPY5R Q15761 2/20 0.33
EDNRB P24530 1/20 0.33
EDNRA P25101 1/20 0.33
GFER P55789 1/20 0.33
AKR1C4 P17516 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18020031 0.96 L3MBTL1 (0.51) KDM4EL3MBTL1ATMALKBH5FTO
SCHEMBL25925512 0.94 L3MBTL1 (0.46) KDM4EL3MBTL1ATMALKBH5FTO
SCHEMBL19001881 0.89 ALKBH5 (0.41) KDM4EL3MBTL1ATMALKBH5FTO
SCHEMBL23615513 0.89 KDM4E (0.39) KDM4EL3MBTL1ATMALKBH5FTO
SCHEMBL15248201 0.88 KDM4E (0.41) KDM4EL3MBTL1ATMALKBH5FTO
SCHEMBL19558184 0.88 KDM4E (0.49) KDM4EL3MBTL1ATMALKBH5FTO
SCHEMBL26472552 0.88 L3MBTL1 (0.55) KDM4EL3MBTL1ATMPTGER4TSPO
SCHEMBL20878493 0.87 L3MBTL1 (0.47) KDM4EL3MBTL1ATMALKBH5FTO
SCHEMBL24994007 0.86 ALDH1A1 (0.41) KDM4EL3MBTL1ATMALKBH5FTO
SCHEMBL23622096 0.86 KDM4E (0.44) KDM4EL3MBTL1ATMALKBH5FTO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023142486-A1 BORON-NITROGEN COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF 季华恒烨(佛山)电子材料有限公司 2023-08-03 WO disclosed