Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.49 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.49 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21954408 | 0.89 | GAA (0.72) | MAPTPKMLMNAL3MBTL1GAA | |
| SCHEMBL8795754 | 0.87 | ALOX15 (0.61) | MAPTPKMALOX15 | |
| SCHEMBL25255940 | 0.86 | MAPT (0.49) | MAPTPKMLMNAL3MBTL1GAA | |
| SCHEMBL25175645 | 0.85 | NR4A2 (0.63) | MAPTPKMLMNAL3MBTL1GAA | |
| SCHEMBL9938004 | 0.83 | GAA (0.60) | MAPTPKMLMNAL3MBTL1GAA | |
| SCHEMBL23606247 | 0.83 | GAA (0.60) | MAPTPKMLMNAL3MBTL1GAA | |
| SCHEMBL16344846 | 0.83 | ALOX15 (0.70) | MAPTPKMLMNAL3MBTL1GAA | |
| SCHEMBL31422791 | 0.82 | GABRA1 (0.49) | MAPTPKMLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL16344594 | 0.81 | PTGS1 (0.60) | MAPTPKMLMNAL3MBTL1GAA | |
| SCHEMBL24074581 | 0.80 | ALDH1A1 (0.58) | MAPTLMNAGAAALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4209492-A1 | COMPOUND FOR TREATING THROMBOTIC DISEASES | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2023-07-12 | — | — | EP | disclosed |