Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.46 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.44 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.44 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.44 |
| ▸ | RRM1 | P23921 | 1/20 | 0.43 |
| ▸ | TLR2 | O60603 | 2/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23589454 | 0.82 | SIRT6 (0.52) | SIRT6SIRT1DPP7GNAI3GNAO1 | |
| SCHEMBL26379449 | 0.82 | SIRT6 (0.40) | SIRT6SIRT1DPP7GNAI3GNAO1 | |
| SCHEMBL14230379 | 0.80 | CA1 (0.44) | DPP7EPHX1 | |
| SCHEMBL24308138 | 0.77 | SIRT6 (0.41) | SIRT6SIRT1DPP7GNAI3GNAO1 | |
| SCHEMBL1753873 | 0.76 | DPP7 (0.60) | DPP7GNAI3GNAO1GNAI1RRM1 | |
| SCHEMBL16283727 | 0.75 | TLR2 (0.45) | SIRT6SIRT1DPP7GNAI3GNAO1 | |
| SCHEMBL24072564 | 0.74 | EPHX1 (0.61) | DPP7GNAI3GNAO1GNAI1RRM1 | |
| SCHEMBL11035085 | 0.74 | EPHX1 (0.61) | DPP7GNAI3GNAO1GNAI1RRM1 | |
| SCHEMBL25454649 | 0.74 | EPHX1 (0.61) | DPP7GNAI3GNAO1GNAI1RRM1 | |
| SCHEMBL16410230 | 0.74 | EPHX1 (0.61) | DPP7GNAI3GNAO1GNAI1RRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230331801-A1 | IL-2R-BETA-GAMMA BINDING COMPOUNDS | MEDIKINE, INC. (US) | 2023-10-19 | — | — | US | disclosed |
| US-11718654-B2 | IL-2R-βγ binding compounds | MEDIKINE, INC. (US) | 2023-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230331801-A1 | IL-2R-BETA-GAMMA BINDING COMPOUNDS | IL2RA, IL2, IL15RA | SIRT6 4196/4885SIRT1 3438/4885DPP7 2427/4885 |
| US-11718654-B2 | IL-2R-βγ binding compounds | IL2RA, IL2, IL1RN | SIRT6 4125/4885SIRT1 3372/4885DPP7 2337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.