Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25299062 | 0.76 | SLC6A2 (0.47) | KDM1AMAOBSLC6A3 | |
| SCHEMBL29497057 | 0.76 | SLC6A2 (0.47) | KDM1AMAOBSLC6A3 | |
| SCHEMBL20757589 | 0.75 | TRPV4 (0.46) | KCNH2SLC6A3TAAR1 | |
| SCHEMBL31484342 | 0.75 | TRPV4 (0.46) | KCNH2SLC6A3TAAR1 | |
| SCHEMBL29497099 | 0.73 | SCN9A (0.43) | KCNH2 | |
| SCHEMBL25295868 | 0.73 | SCN9A (0.43) | KCNH2 | |
| SCHEMBL23176457 | 0.68 | CHRNB2 (0.40) | SLC6A3 | |
| SCHEMBL20757258 | 0.65 | HTR2C (0.66) | — | |
| SCHEMBL20281953 | 0.65 | HRH4 (0.43) | KDM1A | |
| SCHEMBL20757967 | 0.64 | HDAC4 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023144160-A1 | NEW HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-08-03 | — | — | WO | disclosed |